Cord injury

Research on Spinal Cord Injuries A frightening 2.5 million people live with the burden of a spinal cord injury. Each year, more than 130,000 new injuries are reported (Oyinbo, 2011). A spinal cord injury is one of the most debilitating injuries, and puts a lifelong burden on not only the patient, but the caregiver as well. Years ago, a spinal cord injury translated to a lifetime of wheelchair confinement, endless comorbidities, and lost hope of ever regaining normal function. Treatment was limited

A spinal cord injury does not occur in a single moment. Instead damage will continue to ensue for days to weeks after the initial injury. The initial impact and injury causes the immediate damage and death of oligodendrocytes and motor neurons. However, another wave of damage is caused by the secondary processes that occur after the injury. The spinal cord is a bundle of nervous tissue and neurons protected by the vertebral column that transmits electrical synapses, or messages, from the brain to

primarily with spinal cord injury, also known as SCI. Each spinal cord injury is different and any damage to the spinal cord is a very complex injury and most devastating of all traumatic events. Damage to the spinal cord can occur from either a traumatic injury or from disease to the vertebral column. A person’s injury is described by its level and type, which may result in a loss of some or all of an individual’s sensation and movement. The higher the spinal cord injury is on the vertebral column

Background and Rationale: Spinal cord injury (SCI) is a devastating and debilitating condition caused by a traumatic blow to the spine. SCI is irreversible, leaving many patients with permanent loss of motor function as a result of neuronal injury, including nerve compression, myelin sheath loss, nerve disconnection, and nerve degeneration (Fig. 1) [1-3]. The annual incidence of SCI in the United States is approximately 12,000 new cases each year [1, 5]. With the aging population and increased occurrence

Many spinal cord injuries (SCI) patients are suffering from the impairment of impulse conduction and they are unable to carry out their activities of daily living. Rehabilitation becomes an important role in enhancing motor recovery and minimizing the deficits of their movement function. The goal of this research is to deliver natural gait behavior of a rat through active robotics and intelligent system for the SCI Sprague-Dawley rat. The advance of this research is not only the rehabilitation novel

I. Spinal cord injury, Stoke, TBI A. Goal: 1. Regain functional gait through partial weight-bearing therapy. B. Method: 1. Initial removal of 40% of patients body weight until patient exhibits gait symmetry on treadmill 2. Increase body weight patient must ambulate with on treadmill with symmetry in gait until a reduction of 20% has been achieved 3. Patient is now able to ambulate on treadmill with gait symmetry at 20 % body weight reduction; speed may be increased to develop functional step speed

spinal cord injury (SCI), and 99.6% of these individuals are paralyzed to some extent.1 SCI is the result of a mechanical insult to the spine that damages the spinal cord. This is followed by secondary SCI, which involves a series of biochemical events resulting in further neuronal and glial cell death.2 Astrocytes, the most abundant glial cell of the central nervous system (CNS), provide neurons with structural and neurotrophic support as well as protection from toxins. Following primary injury, damaged

Induce Induction of spinal cord injury Female Sprague-Dawley rats at 8 weeks old were used for all experiments. Rats were anesthetized with an intraperitoneal injection of phenobarbital sodium (35 mg/kg) and placed prone on a heating pad to maintain a constant body temperature. Modified NYU weight-drop model was performed for spinal cord injury (SCI). A laminectomy was performed at the T10 level. The spinous processes of T8 and T11 were then clamped to stabilize the spine, a 10-g weight (3-mm diameter

When you hear the term ‘spinal cord injury’ you often associate this with something permanent, irreversible and extremely detrimental to the life of the individual affected. Recent studies into the application of induced pluripotent stem cells have found a way to potentially cure this condition, with the grafting of iPS cells to the human spine. It is impossible to argue with the results of recent research studies, which clearly demonstrate its capability to treat this condition. However, there

Approximately 11,000 new cases of spinal cord injury (SCI) occur in the United States each year, contributing to the over 200,000 individuals currently living with SCI. SCI results in tremendous changes in an individual’s life, causing impairments to the musculoskeletal, cardiopulmonary, integumentary, gastrointestinal, genitourinary and sensory systems. Mobility and self-care become limited as well as participation in social and everyday activities when SCI causes paralysis of the muscles below