Cytogenetics

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    Sickle-cell disease Chenglie Nanjie Sickle cell disease is a kind of disease that contains a group of disorders that affects hemoglobin, the oxygen-carrying molecule in red blood cells that transfers oxygen to cells (U.S. NIH, 2012). A particular mutation in the HBB (hemoglobin, beta) gene causes sickle cell anemia, a common form of sickle cell disease (U.S. NIH, 2014). Sickle cell disease can lead to various symptoms. Most significantly, it leads to very acute and chronic pain as well as organ

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    Fragile X Syndrome • Etiology (cause) – Fragile X Syndrome is inherited. Fragile X is caused by a mutation of the X chromosome in the FMR-1 gene. This specific mutation is an expansion or lengthening of the gene. The X chromosome is one of two chromosomes that determines the sex of a person. When this gene lengthens, it prevents production of a protein that is involved with brain development and other important functions of the body. In a typically developing human, the FMR-1 gene duplicates

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    Telome Fusion

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    single telomere can result in fusion of sister chromatids (Sabatier et al., 2005). This type of chromosome rearrangement is more difficult to monitor than ring or dicentric chromosomes, because sister chromatid fusions are not detectable by routine cytogenetic analysis. As first described by McClintock, sister chromatid fusion can result in prolonged CIN involving breakage/fusion/bridge (B/F/B) cycles. B/F/B cycles occur when the fused sister chromatids form a bridge during anaphase and then break when

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    Cell Myeloma Essay

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    1.Title: Prognostic impact of MYC rearrangement in progression of plasma cell myeloma Introduction Acquired chromosomal abnormalities are considered as an important prognostic marker in several hematologic malignancies. Cytogenetic aberrations play an important role in pathogenesis of disease and survival outcome. Here, our goal is to study the prognostic impact of Myc abnormalities and their role in progression of multiple myeloma. The study will also include cyclinD1 gene rearrangement; the most

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    is a physician who examines tissues, checks the accuracy of lab tests, and interprets the results. Recognized subspecialties include chemical pathology - also called clinical chemistry - clinical, hematology, transfusion medicine, microbiology, cytogenetics, and molecular

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    Satire Essay On Nature

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    Imagine you had to live in a cage for your entire life with no control over anything you do. Imagine having no control over when you eat or what do you do in your spare time. This is how millions of animals who are used in laboratories feel every second of their short life. Humans usually have this dreadful habitude of assuming we’re superior to all other living beings on earth. Since the dawn of time, we’ve always had this notion that nature is inferior to us. Now more recently than ever, we’ve

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    College Essay On Leukemia

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    Leukemia Types, Causes, and Treatment Leukemia, or blood cancer, is a rare but serious disorder, development and cause of which is not well understood even today. In United States, leukemia affects approximately 200,000 new patients every year. The survival rate varies greatly depending on the type of leukemia a person has, the age of the patient, and time of the diagnosis. The ability to treat leukemia depends greatly on the proper diagnosis and the selection of appropriate treatment protocol.

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    of Horticultural Sciences. Dr. Chen’s researches plant cytogenetics to discern the molecular genetic pathways in meiotic recombination with Arabidopsis and horticultural crops. Beginning as a field and greenhouse assistant, I attended laboratory meetings to gain exposure to experimental design and molecular genetics techniques, such as genome editing techniques with

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    prefer one department over the others and wish to learn all they can about it. The first way to do this is to obtain a specialist certification. These specialization include: chemistry, hematology, microbiology, blood banking, molecular biology, and cytogenetics. This certification is similar to obtaining a medical laboratory science certification, since both require the technician to pass a test. With these certifications the laboratory scientist have more say in the overall workflow in that department

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    Abstract: The pre- and post- treatments effects of Habak, one of Mentha longifolia subspecies, as one of the famous folk medicine was studied in mouse bone-marrow cells in contrary to the mutagenicity of cyclophosphamide (CP). Male Balb/C mice were pre- and post-treated orally with aqueous extract of Habak at variable concentrations (250, 500 and 1000 mg/kg b.wt) for 24h and 48h respectively. Mice were injected intraperitoneally with CP for 24h pre- and post-treatment with Habak. Assessment of cell

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