Developmental biology

have developed a passion for developmental biology through research and coursework at The University of Texas at Austin. Through my research, I have grown a deep appreciation for the complex integration of genetics, cell biology, and tissue-level events that contribute to the formation and growth of a living organism. The interdisciplinary nature of the field, coupled with the training I have received as an undergraduate lead me to believe that developmental biology would be an optimal area of study

transition to University of Michigan. Academically speaking, my adventurous and skeptical nature allows me to identify and understand exactly what I intellectually need, and easily contrast that with my wants and capabilities. Genuine intrigue in developmental biology is what makes UROP’s Biomedical Research Fellowship perfect for me. Many laboratories are searching for summer interns.

Elizabeth Ables is an assistant professor at East Carolina University, in Greenville, North Carolina. She has worked there since 2013. Dr. Ables received her BS degree from St. Andrews University and her Ph.D. in Molecular Physiology and Developmental Biology from Vanderbilt University. She studied how the pancreas precursor cells are led by a cascade of transcription factors during development to become insulin-producing beta cells, while using transgenic mice and immunofluorescence microscopy

limited capacity as a model system for understanding the developmental events that support the initiation and maintenance of human pregnancy. Human ES cell lines thus provide an important new in vitro model that will improve our understanding of the differentiation

Generation of pattern and diversity in Central Nervous System Central nervous system (CNS) is composed of brain and the spinal cord. Neurons constitute a major part of the developing CNS. An axon is an extension of a neuron. The brain grows as a swelling at the front (rostal) end of the neural tube and later leads to become a spinal cord (1,2). Development of the CNS involves many complex mechanisms beginning at the onset of transformation of a single layer of ectodermal cells, the neuroectoderm

genes responsible for mesoderm layer in cnidarians were repressed leading to the loss of the mesoderm. Developmental biology experiment to test hypothesis: The experiment would start with an exploration of the gastrulation stage of the ctenophores, cnidarians, and bilaterians. In the proposed stage, germ layers should be clearly identified. If ctenophores and bilitarians have a similar developmental pattern, the genes that regulate the expression of both mesoderm layers should be identified. With the

Lab-grown mini lungs successfully transplanted into mice Date: November 8, 2016 Source: University of Michigan Health System Summary: Scientists can now grow 3-D models of lungs from stem cells, creating new ways to study respiratory diseases, report scientists. Share: FULL STORY ________________________________________ Jason Spence, Ph.D. has grown 3-D models of various organs from stem cells, creating new ways to study disease. (Stock image) Researchers at the University of Michigan have transplanted

anterior-posterior (AP) axis. Homeoproteins are the ultimate regulators of development; however – mutations in the homeobox genes – specifically – HOXC10 are oncogenic (by gain-of-function mutations) and aid in the proliferation of certain cancer types and developmental disorders. Elucidation of HOXC10, its function in embryonic development at the molecular level, and characteristics shared among the function(s) of its paralogues should allow for better understanding of HOXC10’s role primarily

Understanding the biology of early life history stages of fish is essential for effective fisheries management (Mwaluma et al., 2014; Hames Hichford, 2005). For example, knowledge in fish development such as ontogenetic intervals and embryonic and larval development of fish species is a prerequisite to set the policies for their conservation and stock enhancement through larviculture (Rahman et al, 2009; Yanes-Roca et al., 2012; Amini et al., 2015; Andrade et al., 2016). Furthermore, the mechanisms

Introduction Every year, thousands of individuals worldwide are affected by Spinal Cord Injury (SCI), a devastating neurological disorder that, unfortunately, remains without an effective therapy, since the current approved approaches are essentially palliative1. Several types of new therapeutic strategies, including cellular, molecular and combinatorial approaches, have been studied in the recent years. Cell therapies, aiming particularly at replacing lost neurons and recovering the neuronal