Diabetic nephropathy

Diabetic Nephropathy or Diabetic Kidney Disease is a syndrome that has been generally defined as disease in which there is increased protein excretion in urine. It is commonly characterized by the presence of pathological quantities of albumin in urine that is excreted from the patient’s body, diabetic glomerular lesions, and loss of glomerular filtration rate (GFR) in diabetics. It can be categorized into stages: microalbuminuria and macroalbuminuria. The early stage is usually characterized by

What causes diabetic nephropathy (kidney disease)? By Jonas Wilson, Ing. Med. Kidney disease and diabetes tend to go hand in hand as the kidneys of diabetics slowly thicken and become progressively scarred over time. The nephrons, which are the basic functional and structural units of the kidneys, become leaky and allow albumin, a protein made by the liver, to pass freely into the urine. The damage to the kidney may be ongoing for many years before a patient becomes symptomatic and loses the ability

Diabetic Kidney Disease Diabetic kidney disease (DKD) is defined kidney disease attributed to diabetes (versus chronic kidney disease, which may be due to numerous etiologies including diabetes). ADA recommends screening for nephropathy 5 years after diagnosis for type 1 diabetes and at diagnosis for type 2 diabetes. Screening includes urine albumin excretion (albumin/gr creatinine). ADA no longer uses the terms “micro (< 30 ug/mg Cr) and macroalbuminuria (> ug/mg Cr)”, but defines albuminuria

Diabetic nephropathy (DN) refers to a characteristic set of structural and functional kidney abnormalities in patients with diabetes.1 It is the most important long-term complication of diabetes mellitus (DM). It is a progressive condition with high cardiovascular morbidity and mortality. It progresses in both Type 1 and Type 2 diabetes in a relatively predictable manner through the stages of normoalbuminuria, microalbuminuria and macroalbuminuria which often heralds increasing creatinine as the

Daniel Jeffrey On June 3rd we met with a 75-year-old African American female dialysis patient who is in renal failure due to a long history of hypertension, and type II diabetes leading to diabetic nephropathy. Diabetic nephropathy is caused by the blood glucose rising beyond the filtration capacity of the kidneys; they then lose their abilities to reabsorb glucose. The increased volume dilutes the NaCl in the urine, signaling the macula densa to release renin, causing vasoconstriction. Because

During my first clinical rotation I was assigned a patient who, down to his last kidney, was living with end stage renal disease. I noticed quickly that this man, one of ethnical minority, relied on his family members to give him information and advice pertaining to his treatment, as he himself seemed ignorant to his own medical problems. I found his case fascinating, as he not only had one kidney, but he was also suffering many other debilitating medical crisis’, all brought on by his failing renal

Iwill be analyzing Case Study 2.3 from unit two in the study guide. The professional ethics issue in this case is: “Whether the doctor should lie to the family regarding the father’s ability to donate a kidney and begin a search for a cadaver kidney?” This is an important and controversial question, which is discussed in this essay. There are two possible answers, “yes” and “no” to this question asked, and each side is analysed. I will discuss both possible outcomes to the professional ethics question

Imagine yourself sitting on the examination table at your doctor’s office, you have been experiencing nausea, fatigue, appetite loss, muscle cramps and other symptoms for the past couple months or so. Today is the day you will finally get your bloodwork results back, the overwhelming fear of the unknown will finally be put to rest. Your mind is racing with the never ending possibilities of life threatening illnesses but you try and remain calm, convincing yourself that everything will be ok. The

incidence and severity of diabetic nephropathy. The likelihood of developing diabetic nephropathy is markedly increased in patients with a diabetic sibling or parent who has diabetic nephropathy. Age — For type 1 diabetes, the risk of developing ESRD is very low for patients diagnosed prior to age 5; at older ages, the relationship of age to progression to ESRD is uncertain Blood pressure — Higher blood pressures have been noted to be associated with diabetic nephropathy. Obesity — A high body mass

Diabetic nephropathy, an irreversible kidney failure, continues to be the most common cause of end stage renal disease requiring either a kidney transplant or renal replacement therapies, such as dialysis (Bilous, 2013). Worldwide, approximately fifty percent of cases of end-stage chronic kidney disease are caused by diabetes mellitus, with type II comprising the majority (Vladu, 2014). The prevalence of diabetes has been estimated to increase worldwide with the total number of diabetics rising from