Digoxin

situation and can monitor by means of serum levels of cardiac glycoside, calcium, potassium, magnesium, and through ECG. Digoxin has been a suitable aide treatment to improve signs and symptoms of heart failure, the under dosage of digoxin will cause a continuation of heart failure symptoms, while overdosage may result in toxicity; in cases of severe digitalis toxicity, digoxin immune Fab can be given intravenously to patients (Faye Felicilda-Reynaldo,

fibrillation and with systolic CHF, it promotes to function the left ventricle and controls the heart rate with low ejection fraction ( Caccamo & Eckman, 2011; Katzung, 2012). Pharmacodynamics/ mechanism of action of DG Digoxin and numerous substance of digoxin are the only active metabolite in a small fraction that occurs in the stomach, liver, as well as their metabolic passageway has been recognize (Gault, Longerich, Dawe, M., & Fine, 1994). DG and other glycosides drugs for the heart

Introduction This assignment shall focus on a patient called Audrey Smith, a 75 year old lady who has been transferred to the ward from the emergency department with a fractured neck of femur, small haematoma to the left forehead, soft tissue injury and bruising to the left shoulder following a fall at home involving her dog. On admission to the ward at 14.00 hours, Audrey has an intravenous transfusion in progress, an indwelling catheter insitu, she is alert and orientated to time and place and

Question 1: Digoxin toxicity. Digoxin has a narrow therapeutic index and chronic toxicity is more likely in the elderly and those with renal impairment. Since Mr Buchanan is 75 years old, he may already have some form of renal impairment and therefore is at a higher risk of developing toxic serums levels if continually taking Digoxin (Australian Medicines Handbook, 2016 and Nickson, 2014). Digoxin toxicity can be caused by prolonged use, an overdose or a general increase in the current dose (Australian

digitalis by slowing the heart rate in atrial fibrillation patients (1). Digoxin was the cornerstone for atrial fibrillation until verapamil was discovered in1967; which shown to be effective in slowing the ventricular rate in atrial fibrillation by Bender, et al..(2). In 1980, Klein and colleagues wrote a letter to the editor to report their experience with verapamil-digoxin interaction that result in increased serum digoxin concentrations (SDC) by 58% (3). Belz and colleagues published the first

Digoxin Oluchi Madubuike University of Texas at Arlington Pharmacology and the Nursing Process N3365-001 Sandra Laird April 1, 2015 OVERVIEW OF DIGOXIN Origin Digoxin is a drug gotten from the leaves of a digitalis plant ("Digitalis," 2015, para. 1). We commonly refer to this plant as foxglove but we also use its botanical name, which is Digitalis purpurea when discussing it ("Digitalis," 2015, para. 2). Foxglove is a popular flower that can be found growing along the roadsides and in meadows or

digitalis by slowing the heart rate in atrial fibrillation patients (1). Digoxin was the cornerstone for atrial fibrillation until verapamil was discovered in1967; which shown to be effective in slowing the ventricular rate in atrial fibrillation by Bender and colleagues (2). Klein and colleagues wrote a letter to the editor, in 1980, to report his experience with verapamil-digoxin interaction to result in increased serum digoxin concentrations (SCD) by 58% (3). The first randomized study was published

clinic because he was experiencing atrial fibrillation and had a ventricular response of 110 beats/min with palpitations and shortness of breath1. Medications that he was taking includes angiotensin-converting enzyme inhibitor, Lisinopril, Carvediol, Digoxin, and Furosemide1. His left ventricular ejection fraction has been reduced to 25%1. Further examinations showed that he had edema in his legs and crackles at the base of his lungs1. He was then told to increase the dosage of Furosemide by taking the

left ventricualr ejection fraction, stroke volume, pulmonary capilary wedge pressure and exercise tolerance (33). Secondly, digoxin produce vagus activation showing negavite chronotropic action in SA node and negative dromotropic action in AV node. This lead to a shift in automatic balance by dominating the positive iontropic action of the drugs digoxin (33). In this way digoxin is cosinder as a only available inotropic drug which increase cardiac output and decreae pulmoary capillary wedge preure with

Janice Estrella, her autopsy showed high Digoxin level. Digoxin is a controlled drug that increase circulation and slows heart rate. Next victim happened in March of 1981 his name was Kevin Pacsai only twenty-three days old even though his condition wasn’t even life threatening, however the nurse failed to convince the doctors to attend to Kevin Pacsi even though he was struggling the morning of his death. Kevin’s autopsy came back and showed high dosage of Digoxin. After Kevin Pacsai and Janice Estrella