Dimer

were completed on Lucy including a troponin, d-dimer and coagulation screening. Troponin is a protein released into the bloodstream after injury to the cardiac muscles (Brown & Edwards, 2012). This test is completed to determine if there is any heart muscle damage but is not a definitive diagnoses as a raised troponin can be caused by many conditions including pericarditis, myocardial infarction or surgery (Korff, Katus, & Giannitsis, 2006). A d-dimer is a fibrin degradation product used to determine

be repaired (photoreactivation, post-replication repair & excision repair), whereas in prokaryotes excision repair mechanism is used. - Explain how do pyrimidine dimers form. Pyrimidine dimers form when DNA is damaged by UV light and they form

probability with Wells Prediction Rule 6, 1 o If low probability, perform D-dimer testing • D-dimer negative, no further work-up • D-dimer positive, obtain venous ultrasound • Ultrasound normal, no further testing • Ultrasound abnormal, treat o If high probability of DVT, perform venous ultrasound • Ultrasound abnormal, treat for deep vein thrombosis • Ultrasound normal, perform D-dimer testing • D-dimer negative, no further workup • D-dimer positive, repeat ultrasound in 7 days, or perform venography 2, 4

diseases such as XP. This disease is mostly linked with the inability to repair cells that contain photoproducts in your DNA that is initiated by UV light. These photoproducts include the (5–5) and (6–6) cyclobutane pyrimidine dimers (CPDs) and the (6–4) pyrimidine pyrimidinone dimers (PDs) that can involve T and C pyrimidines [7]. As these DNA are not repaired due to the lack of NER proteins, a mutation will occur which will substitute a Cytosine base to a Thymine base, it is most common when there are

A naturally endocannabinoid in our bodies is called anandamide, which in Sanskrit means “a blissful amide” and is also found in other species including birds, reptiles and fish. Since our bodies produce their own form of “natural THC”, however tiny the amount, it is logical that humans are so drawn to marijuana’s herb! Both THC and anandamide produce their effects through lipid receptors, known as cannabinoid receptors, located on the cell surface throughout our bodies and have similar effects on

gamma-tubulin subunits forming an open ring where the first set of tubulin are added at the positive end (Tassins and Bornens, 1999). Growth of the microtubule consists of the polymerization, addition of tubulin dimers on the positive end near the cell periphery, faster than tubulin dimers can be lost at the minus end, which is attached to the centrosome toward the cell center.

within the restricted boundaries of a single cell. Core histones (H2A, H2B, H3 and H4) and Linker histones (H1) are the two types that this unique protein is composed of. These Core histone exhibit a structured organization with H2A and H2B forming dimers and H3 and H4 forming tetramers. Along with approximately 146 base pairs of DNA, these core histones form a heterotypic nucleosome complex; weighing about 206

The dynamic light scattering data showed two distinct peaks, suggesting that the NDM-1 enzyme exists as both a monomer and dimer in solution. According to the supplemental data, the radium for the monomer was about 2.8 nm, while that for the dimer was about 3.5 nm. The dimer was also roughy twice as heavy as the monomer (37 kDa vs 62 kDA), suggesting that it indeed was a monomer, and not a different protein. The amino with the unusual torsion angles

ariam Alam U0828912 #1 OBSERVATIONS: I remember in my high school Biology class we learned that some Ultraviolet Exposure is good for our health, which led me to wonder why certain wavelengths of radiation are harmful while others are not. #2 QUESTIONS: Why are certain wavelengths (gamma rays & X-rays) of radiation damage DNA and not others? Can DNA be repaired when damaged? #3 HYPOTHESIS: Some wavelengths of radiation are more harmful due to difference is energy and photons which may

of blood coagulation and damage to the endothelial lining of the vein (Patel, 2015). The result is increased viscosity of circulating blood and the formation of thrombus. The blood test that is used to determine the presence of DVT is D-dimer. The level of D-dimer remains elevated for 7 days after the formation of a DVT. Blood tests of prothrombin time and partial prothrombin time are also obtained to determine coagulopathy. The gold standard for the diagnosis for DVT is a Doppler ultrasound of the