Electrospinning is a convenient method for fabricating various nanofibrous scaffolds for biomedical applications. In electrospinning process, a conductive collector device plays a critical role in determining the shape and the structure of the nanofibrous scaffold; however, the preparation of the collector is often complex. In this study, a novel, flexible, and inexpensive approach based on pencil-on-paper method was developed for preparing collectors used in electrospinning. Graphite is a conductive
Nanofibers are a stimulating new class of material used for a couple of regard included applications, for instance, remedial, filtration, deterrent, wipes, singular care, composite, pieces of attire, assurance, and essentialness amassing. Extraordinary properties of nanofibers make them sensible for a broad assortment of employments from therapeutic to client things and current to bleeding edge applications for avionics, capacitors, transistors, sedate transport structures, battery separators, essentialness
The main technique that will be used during this project is electrospinning nanofibers. The goal of electrospinning is to produce polymer fibers so that their diameters are much smaller, on a nano-scale size. Electrospinning fibers is a relatively cost effective and simple set-up (Pham, 2006) as shown in Figure 1. Figure 1: Shows an example set-up that contains a syringe, a collector and designates the controlled variables of applied voltage (V), distance between the tip and the collector, and
Recently, the method of electrospinning by heat treatment has received significant attention owing to its simplicity, high efficiency, and versatility for the preparation of diverse one-dimensional structures. For example, Zhao’s group fabricated the composite film electrode of MnO/Carbon through incorporating MnO2 nanowires from hydrothermal into polymer solution by a facile electrospinning technique. The MC-800 membrane exhibited a high reversible capacity of 987.3 mAh g −1, after 150 cycles at
Preparation and Characterization of Electrospinning Fluorine-doped Tin Oxide for Solar Applications. Shaker Ebrahim, Marwa Adel a, Moataz Soliman Department of Materials Science, Institute of Graduate Studies and Research, Alexandria University, P.O Box 832, Egypt a Department of Physics, Faculty of Science, Alexandria University, Egypt Abstract Transparent conductive films of fluorine doped tin oxide (FTO) electrospun on glass substrate were prepared. These transparent conductive films were prepared
Introduction Atherosclerosis is an inflammatory disease that causes formation of plaques under the intimal layer of the blood vessel wall. As the plaque grows and calcifies, it narrows the blood vessel lumen and decreases blood flow to the downstream tissue. Also, risk of plaque rupture increases. Plaque rupture leads to platelet adhesion that results in a thrombus, which occludes the artery. Occlusion of the coronary arteries results in myocardial infarction. Pathologies affecting small and medium
bioactive molecules in a synthetic scaffold is very important to mimic the natural ECM. In general, there are two ways to add bioactive molecules to a scaffold. This can be done by either mixing the bioactive compounds and the polymers used for electrospinning or introducing covalent modifications to the polymers. Mixing bioactive compounds and base materials often result in a highly dynamic but uncontrollable release of bioactive molecules. Covalent modifications result in stable incorporation of bioactive
Electrospinning Electrospinning uses an electric field to control the formation and deposition of polymeric fibers onto the targeted surface or substrate [181-183]. In this method, a polymeric solution is injected with a specific voltage that generates a potential difference between the polymeric solution and the targeted substrate. This lead to the ejection of the polymeric fluid from a tip of the capillary or a spinneret when the electrical charges overcome the surface tension of the fluid. As
Neurotrophin-3 (NT-3). Positively charged polyethylenimine (PEI) will be complexed with negatively charged Ψ-mRNA in order to preserve the genetic material’s bioactivity as well as enable transfection of cells.8 I will fabricate this scaffold by electrospinning PEI/Ψ-mRNA polyplexes into aligned poly(lactide-co-ε-caprolactone) (PLCL) fibers that will provide sustained, localized release of the polyplexes and promote directional regeneration of axons. Aim1: Synthesize Ψ Modified NT-3 mRNA Hypothesis:
report, I have mentioned three such autologous biomaterials; albumin, collagen and B.mori silk fibroins, which are easily available and possesses the desired properties to manufacture scaffolds from them. I manufactured scaffolds by the process of electrospinning and tested the porosity and swelling of the scaffolds. Introduction Tissue engineering is a field where scientists try to repair or regenerate damaged tissues or cells with the help of artificial materials. In layman’s term, tissue