Elimination reaction

In this lab, the goal is to explore the idea of elimination reactions and investigate ways to synthesizes alkynes. The product that will be produced is diphenylacetylene and this will be done by starting with meso-stilbene dibromide using elimination reactions. The balanced reaction is: For an E2 reaction to occur, strong bases should be utilized for this lab since E2 reactions favor well with strong bases. KOH is a strong base that is also acts as a strong nucleophile. This is because it contains

Substitution and Elimination Reactions Substitution reactions replace a functional group with a new group. These reactions compete with elimination reactions in which a group is eliminated and a π (pi) bond is formed. Substitution reactions occur when a nucleophile is added to an electrophile/substrate. Elimination reactions occur when a base is added to an electrophile/substrate. The electrophile must contain a leaving group to be considered a substrate. Alkyl Halides Alkyl Halides are the common

Elimination Reactions of Alkyl Halides Purpose The purpose of this lab is to understand the process of eliminating an alkyl halide to form an alkene. The experiment is carried out by first converting the alcohol, 2-methy-2-butanol, into the alkyl halide of 2-chloro-2-methylbutane that will then be put through dehydrohalogenation that favors elimination reaction (E2) to create a mixture of 2-methyl-2-butene and 2-methyl-1-butene. A fractional distillation will be taken to purify the mixture and an

Introduction An elimination reaction is when an atom or group of atoms, the leaving group, leaves the molecule along with the loss of a hydrogen atom that is part of an adjacent carbon that results in an alkene (Ketcha, 98). Dehydration is an example of an elimination reaction. Just likes its opposite (hydration, the addition reaction), it could also result in multiple products: one product would be “major” where it is one that was mostly form as it is mostly stable, and one is the “minor” which

Introduction An E1 (unimolecular elimination) reaction is an organic reaction where two groups are removed from the starting molecule in a two-step mechanism. The first group that leaves forms a carbocation intermediate, and the second group that leaves causes the formation of a double bond1. The formation of the carbocation ion in the intermediate is important because that determines the rate of the reaction. If a more stable carbocation can be formed, shifts may occur because the more stable the

initiate the acid-catalyzed dehydration reaction and also promotes rearrangement. The next step was distillation, which functioned to separate liquids based on boiling points. The distillation utilizes boiling points to separate the alkyl halide products from many impurities that might exist. Reflux is the first step instead of distillation because refluxing allows the reaction to progress. If distillation was performed first, separation would begin before the reaction was allowed time to

Horssen CHMY 321 TA: Michael Giroux 10/31/17 Introduction: The purpose of this lab was to carry out a dehydration reaction of 2-methylcyclohexanol by heating it in the presence of phosphoric acid and determining which alkene product would be the major product. Methylcyclohexanols were dehydrated in an 85% phosphoric acid mixture to yield the minor and major alkene product by elimination reaction, specifically E1. The alkenes were distilled to separate the major and minor products and gas chromatography

Section 40 March 27, 2018 Introduction: For this week’s experiment, involved nucleophilic substitution of SN1 and SN2 reactions. On two separate days, SN2 was done first followed by SN1 being done in the next lab. The substitution of one group from a saturated sp3 hybridized carbon atom is typically a reaction that is used to interconvert different functional groups. In this reaction in particular, nucleophiles have the property of having at least one lone pair of electrons (not shared) having either

using cyclohexanol to obtain cyclohexene. This acid-catalysed reaction involves E1 elimination mechanism. The dehydration of alcohol will remove OH- from cyclohexanol to form cyclohexene. Cyclohexene contains a single double bond in the molecule. It is a six carbon aromatic hydrocarbon. Phosphoric acid is mixed with cyclohexanol in the round-bottomed flask and is heated. The phosphoric acid act as a catalyst that increases the rate of reaction but it does not change the overall stoichiometry. The acid

used to identify the product or products for each reaction: 1a, 1b, and 2. Every individual in the group was assigned either 1a (1-propanol) or 1b (2-pentanol), and 2 (1,4-dimethyl-3-pentanol). The purpose of this experiment was to understand and become familiar with the reaction mechanisms and be able to observe and compare the product or products for each of the reactions using 13C NMR and IR.