Epidermal growth factor receptor

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  • Informative Speech For Lung Cancer

    1568 Words  | 7 Pages

    four minutes to explain the cure for lung cancer. It is just to0 vast of a subject. That is why we are going into detail for a specific area of lung cancer. This is all about targeted Therapy. So what is this EGFR gene. EGFR stands for Epidermal growth factor receptor. It is composed of C22H23N3O4. It has a molar mass of 393.436 g/mol. It is located on Chromosome 7 of our cells, with a specific position of 7p11.2. It is responsible for controlling the rate in which cells grow and divide. When this

  • Gastric Cancer Essay

    702 Words  | 3 Pages

    Europe and the United States. Even tough combination therapies have been reported to benefit those with GC, the actual prognosis for GC remains very poor and new treatments are needed (Trastuzumab). HER2 also referred to as ERBB2, is an epidermal growth factor receptor that has growing evidence

  • Aneurysm Essay

    1246 Words  | 5 Pages

    Introduction Despite considerable advances in surgical treatment, the ruptured human abdominal aortic aneurysm (AAA) is still associated with a mortality rate of 65–85% [1, 2] . A diameter is currently the only reliable determinant of the imminent rupture of an AAA and patients exceeding 5.5 cm generally undergo surgical or endovascular intervention [2, 3] . However, the outcome of rupture is poor with less than half of the patients being delivered to the hospital alive [1, 4] . It is well known

  • Role Of The Egf Receptor On Lipid

    2564 Words  | 11 Pages

    The Role of the EGF Receptor LET-23 on Lipid Biosynthesis in Caenorhabditis elegans N. R. Contos Thesis Abstract The Caenorhabditis elegans LET-23, which is an Epidermal Growth Factor (EGF) receptor, controls multiple developmental pathways. In humans, EGF receptor mutations are implicated in a large number of cancers due to excess signaling promoting cell growth and cell division. Recent work has shown that in C. elegans LET-23 may also affect lipid production, specifically that of the phospholipid

  • Radiotherapy's Role In Breast Cancer

    367 Words  | 2 Pages

    genetic factors play an important role in cancer susceptibility [3, 4]. The cumulative effects of individual (non-carcinogenic) chemicals acting on different pathways could produce carcinogenic synergies [5]. Current treatments for cancer include surgery, hormonal therapy, radiotherapy and targeted therapies. Molecular target therapies have a great role in the treatment of cancer, they include inhibitors of the tyrosine kinase enzyme BCR-ABL, inhibitors of vascular endothelial growth factor receptor

  • Skin And The Human Body

    2660 Words  | 11 Pages

    superficial, pigmented, and ulcerative. Risk factors There are any factors that lead to the onset of epidermal carcinogenesis. Ultraviolet radiations play a vital role in developing skin cancer. UV radiations can lead to mutations and alter the signaling pathways. Chances of occurring cancer increases with aging. With respect to this, chances to get SCC is more than BCC. Smoking, alcohol, radiations also contribute to the development of epidermal carcinogenesis. Impaired and suppressed immune system

  • Essay On Non Small Cell Lung Cancer

    1195 Words  | 5 Pages

    management of non-small cell lung cancer also known as (NSCLC). NSCLC should now be further sub-classified by histology and driver mutation if one is known or present. Translational research results now allow such mutations to be inhibited by either receptor monoclonal antibodies (mAb) or small molecule tyrosine kinase inhibitors (TKI). Whilst empirical chemotherapy with a platinum-doublet remains the gold standard for advanced NSCLC without a known driver mutation, targeted therapy is pushing the boundary

  • Development Of Drugs With High Potency And Inhibitory Activity

    1618 Words  | 7 Pages

    of clinical value. an unknown subpopulation of patients with CRC will have an activating EGFR mutation, such as L858R, which is thought to activate the receptor constitutively, regardless of ligand status promoting cellular proliferation and growth. in patients with colorectal cancer, Targeting activated EGFR, hypothetically, will lead to growth inhibition of cancer cell dependent on the oncogenic drive of sensitising EGFR mutation. This project aims to investigate the role of EGFR (L858R/+/+)

  • Epidermal Keeratinocytes Angiogenesis

    684 Words  | 3 Pages

    strengthening of the injured dermal tissue (ie, fibroplasia). Reepithelialization is the process of restoring an intact epidermis after cutaneous injury. It generally involves several processes, including the migration of adjacent epidermal keratinocytes into the wound. Epidermal stem cells from the hair follicle are now thought to originate from the hair bulge that is believed to be the germinative portion of the hair and serve as a reservoir for keratinocytes

  • The Etiology Of Breast Cancer

    946 Words  | 4 Pages

    The etiology of breast cancer is unknown. However, hereditary factors are considered the major determinant of individual in risk. Mutation in cancer susceptibility genes such as BRCA1 can be used in the assessment of individuals at risk of developing breast cancer. Breast cancer initiated as a change in single cell. Progression of tumor depends on accumulation of these changes8. Breast cancers are classified by several grading systems. Histopathology grading depends on the histological appearance

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