Epidermal growth factor receptor

Achondroplasia is one type of short-limbed dwarfism where arms and legs are smaller in length but the head and torso look as if there is no deficiency. The word achondroplasia is derived from the phase "lacking cartilage development." Cartilage is hard and durable but is also a flexible tissue that makes up most of the bone structure during the early stages of development. Nonetheless, in achondroplasia there is no problem with developing cartilage, but instead the problem comes in converting it

Lumpectomy. The lumpectomy is a breast-conserving surgery that removes only the tissue containing the cancer. Lumpectomies are more successful when tumor detection occurs in an earlier stage and smaller size. A patient may opt for a tissue biopsy and lumpectomy simultaneously however, research is dismal in the lifespan impact on this particular surgical approach. Radiation. Radiation therapy can be useful in all stages of breast cancer, however Stage I and II radiation therapy with lumpectomy is

Introduction- Cell-surface receptors are integral membrane proteins that play a major role in signal transduction, allowing the function of Neurons, muscles and sensory organs to occur. Their basic function is to carry out the process of signal transduction by binding to an extracellular signalling molecule. Cell-surface receptors regulate gene transcription, ion flux in the neurons and growth factors. This regulation allows the human body to function with little error. They detect the smallest of

The stages of acute cutaneous wound healing and why some processes may be altered in diabetic patients “The process by which tissue repair takes place is termed wound healing and is comprised of a continuous sequence of inflammation and repair, in which epithelial, endothelial, inflammatory cells, platelets and fibroblasts briefly come together outside their normal domains, interact to restore a semblance of their usual discipline and having done so resume their normal function”. ("The Cellular

regimen in treating metastatic colorectal cancer may improve liver resections. Gia Toan Tang, z3463262. Keywords: Colorectal cancer, liver metastases, resectability, toxicity, tumours. Abbreviations: DLT, dose limiting toxicity; EGFR, epidermal growth factor receptor; mCRC, metastatic colorectal cancer; OS, overall survival; PFS, progressive-free survival. Folprecht’s et al.’s article published in Biomed Central identifies the dosage of a FOLFOXIRI (cetuximab, 5-FU, folinic acid, oxaliplatin and

below it is a bulge area, which houses- Hair follicle epidermal stem cells(HFSCs). Bulge also provides niche for melanocyte stem cells interspersed between HFSCs. Behavior of the two stem cells is well coordinated. Differentiating melanocytes transfer pigment to terminally differentiated hair follicles (Nishimura et al., 2002; Tanimura et al., 2011; Rabbani et al., 2011).Hair follicle undergoes cyclical bouts of 3 phases-anagen (phase of active growth), catagen (destruction phase) and telogen (rest phase)

Breast cancers are classified by several classifications as: - Histopathology - Grades - Stages - Receptor status. Each of these influences the prognosis and can affect treatment response. Description of a breast cancer optimally includes all of these factors: • Histopathology: Breast cancer is usually classified primarily by its histological appearance. Most breast cancers are derived from the epithelium lining the ducts or lobules, and these cancers are classified as ductal or lobular carcinoma

ront of screens (television, computer, game consoles ...), or eating between meals. It is therefore necessary to learn at an early age, and to continue throughout life, to have a varied, balanced diet, with regular meals during the day, so as not to be tempted by snacking. It is also important to learn how to take regular physical exercice. Indeed, even if it does not enable people to lose weight, it allows them to regulate their energy reserves by increasing the use of fats. As we mentioned previously

Monoclonal Antibodies Monoclonal Antibodies (mAB, moABs) are used widely for basic research and hold a great amount of information for medicine, but what are they and how are they formed. What is the main reason we look for monoclonal antibodies? What are its purpose for use? Studies that show these Monoclonal antibodies changed medicine, and how it helped our patients today. How would these monoclonal antibodies change the future in medicine and how we care for our pa- tients. Would we be able to

for newborns and is needed for healthy infant growth and development. In addition, human milk also acts as a conduit for omnifarious immune bioactive factors that facilitate some of the numerous benefits of breastfeeding. Human breast milk consists of rich concentrations of secretory IgA, which works to protect neonates from detrimental viruses and bacteria. Epidermal growth factor (EGF) as well as other growth factors like TGFβ1, and TGFβ2, TNF-receptor I (TNF-RI), and cytokines such as TNFα, IL-6