Epidermolysis bullosa

life was. Unheard of and painful. I felt like nobody else felt this. Ever. I’m sorry, let me introduce myself. Hello. I’m Rebecca Smith but you can call me Rebbie. That’s what my friends call me, if you can even consider them that. I have Epidermolysis Bullosa. I’ve struggled with this my whole life. Basically what it is, is whatever friction there is on my body, it makes me blister. I have very weak tissue in my skin. Every day I beg my mom to let me skip school. In the hallways there are always

Dystrophic EB (DEB), 2) Simplex EB (SEB) and 3) Junctional EB (JEB). These conditions are either caused by autosomal dominant gene mutation or autosomal recessive mutation. DEB can be caused by either of the genes. Another rare form of EB is epidermolysis bullosa acquisita (EBA). It is an autoimmune disorder. This is when the body attacks itself.EBA cannot be inherited. EB can be identified by friction blisters and from EBA. 1.2.1 EB Simplex EB simplex is caused by an autosomal dominant gene mutation

syndrome responded to colchicine therapy. Fever, skin lesions, arthralgias and leukocytosis normalized within 14 days [4]. In another retrospective study of 90 cases, the first-line treatment consisted of colchicine with good results [18]. 4.7- Epidermolysis bullosa

Epidermolysis bullosa first presents itself between birth and early childhood and affects both genders and every race and ethnicity (Mayo Clinic Staff, 2014). When important structural proteins are faulty or not present within the skin of a patient, the skin loses its strength and stability. More specifically, EB Simplex, one of the major subtypes of EB, lacks proper functioning of Keratins 5, 14 and/or a structural protein called plectin in the epidermis (Debra). Since keratin proteins provide

Pathophysiology The COL7A1 gene contains the instruction manual for making proteins that are used for strengthening and supporting the connective tissue in the body which includes tendons, ligaments, bones and skin. “The proteins produced from the COL7A1 gene, called pro-α1 (VII) chains, are the components of type VII collagen.” (http://ghr.nlm.nih.gov/gene/COL7A1) When three pro-α1 (VII) chains twist together, they form a triple-stranded molecule called a procollagen, these molecules are secreted

Jeff Aronin and Paragon Biosciences brings new hope and innovative medical therapies to those suffering from complex medical conditions. He takes prides in bringing innovative products into the healthcare field, for patients who suffer from debilitating medical conditions. Committed to making a difference in healthcare, Paragon Biosciences partners with experts in medicine to bring innovative healthcare to patients who may have very few available treatment options. Thirteen products made exclusively

In the science fiction film Gattaca, Marie and Antonio Freeman, parents of Vincent (the main protagonist) walk into the doctor’s office to design their second child. This is because want Vincent to have a brother, someone to play with. Even though this opportunity is coming close to exist, understanding the “good” and “bad” of making a baby can help decide whether or not to do it yourself. There is the positive side of designing a baby. For instance, when the genetics are screened and the embryo

serology. A skin biopsy can useful in showing typical features of the subepidermal blistering. This is not a confirmation of PG because such blistering may be microscopically similar to that seen in dermatoses such as bullous pemphigoid (BP) or epidermolysis bullosa acquisita

Evil cannot be justified within a theistic framework. Five ideas attempts to argue the existence of evil coincide within a theistic framework. However, all five ideas are flawed and cannot justify how evil can exist within a theistic framework. Counter argument against the five ideas will be discussed below. The first idea argues pain alerts us of danger acting as the body’s warning system. A broken leg would hurt and forces us to leave it alone to heal. However, pain is an imperfect mechanism

Charity shops were once associated with small Creations that were run by volunteers, dealt with second hand goods, remained in the store for a few hours a day and serviced lower income sections of the society. The charity commission defines a charity shop as “a shop which sells donated goods where the income is used for a charitable purpose” (Lekhanya, 2006, p. 6) The essential aim of the charity shop is to raise stores for volunteer funds. The essential working of these shops helps in improvement