Fatal familial insomnia

history. This paper will cover one inherited genetic disease for which there is no cure, Fatal Familial Insomnia ("Self management of Fatal Familial Insomnia. Part 1: What is FFI?", 2006, p. 65). This particular disease was chosen due to its severity, swiftness with which it ends life, and its ability to exist undetected without symptoms for decades unless one’s family history is known. Fatal Familial Insomnia, (FFI), is a neurodegenerative prion disease classified as a Transmissible Spongiform Encephalopathy

and do not consider what might occur to them were they not able to have it; these people would be the envy of the families suffering from the genetic disorder of ‘Fatal Familial Insomnia’. As the name does imply, one who is diagnosed with the extremely rare disease is under a death sentence brought on by progressively worsening insomnia. It is not well-known that sleep deprivation can lead to death, but it has been studied on multiple occasions and it has been very heavily linked with to it [8][9]

Abstract Fatal insomnia, categorized as either familial or sporadic, is an acknowledged rare form of prion disease. Patients express progressively debilitating symptoms which include insomnia, dysautonomia, endocrine disturbance, cognitive dysfunction, and motor abnormalities. A distinct feature of fatal insomnia is the selective atrophy of the thalamus. This and other known cellular changes in fatal insomnia illuminate the diverse functionality of particular brain areas. Similar symptomatic complications

of chronic insomnia, in terms of morbidity and mortality, could explain some of the symptomatic developments seen in FFI and SFI. Perhaps the prion disease itself merely functions to disrupt the sleep wave cycle by damaging the thalamus and all of the other pathophysiology seen in fatal insomnia develops secondary to the insomnia. However, as will be show in the discussion section, there brain regions affected in FFI and SFI are linked to multiple functions! Discussion Fatal insomnia needs development

If you are what you eat, then why is cannibalism bad for you? If you are what you eat, then why is cannibalism so bad for you? Well throughout history, many of us know cannibalism as the consumption of human flesh and meat. But, do any of us really know how it affects our bodies? Studies show that the act of cannibalism in both ritualistic and non-ritualistic practices later turns into generations of life-long deadly diseases. This is all caused by a deadly little prion, which can be referred to

Transmissible spongiform encephalopathies (TSEs), or Prion diseases, are a group of neurodegenerative disorders which include but is not limited to kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker (GSS) syndrome, and fatal familial insomnia in men, natural scrapie in sheep, goats and mufflons. The first records of neurodegenerative disease which would later be linked to Prions were made about two hundred years ago. It was in the 1950’s it was discovered that Prion disease could

rest needed for their brains resulting in physical and mental deterioration. This condition is only found in less than 40 families currently and is hereditary. Sometimes, people can spontaneously develop a non-inherited version called sporadic Fatal Insomnia (sFI). There is no known cure or treatment for this, sleeping drugs is found to have no effect or worsen the

holes while dterteating the neurological functions along with the body (Kuru: The Dynamics of a Prion Disease: Dr. Bindon). Prions are able to come in many deadly forms for example some of the more well known are Creutzfelt- Jakob Disease, Fatal Familial Insomnia, and Kuru which all occur in humans (Kuru: The Dynamics of a Prion Disease: Dr. Bindon). Then there are the ones that occur in animals such as Scrapie, Bovine Spongiform Encephalopathy, Feline Spongiform Encephalopathy, Transmittable Spongiform

Insomnia is a sleep disorder in which can prevent a person from falling asleep or staying asleep. These issues can lead an individual to be unable to get a good night’s rest or feel refreshed the next day because of the poor quality of sleep they get. Based on the National Heart, Lung, and blood institute, insomnia could be diagnosed as a chronic or short term disorder. Individuals diagnosed with insomnia usually have trouble staying awake throughout

disrupt normal activities of cells resulting in their death. Experts believe that fronto-temporal dementia accounts for about 2-10% of all cases of dementia. The symptoms usually appear between the ages of 40 and 65. In some cases, people have a familial history of the disease and in such case genetic factor strongly influences the disease. People with this disorder may live up to 5-10 years after the diagnosis of disease. The frontal and temporal lobes of brain are concerned with judgment and social