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Hypertension is one of the major risk factors for the development of cardiovascular diseases including stroke and may also have a role in the development of vascular cognitive impairment and vascular dementia [1, 2]. Angiotensin I-converting enzyme (EC 3.4.15.1; ACE) plays an important role in the rennin-angiotensin system and it is a carboxyl-terminal dipeptidyl exopeptidase that catalyzes the conversion of angiotensin I to angiotensin II [3-6]. ACE converts an inactive form of decapeptide, angiotensin

it is important to compare UV sensitive yeast cells, which have a mutation that yields them unable to repair themselves, to a wild type that is able to repair itself after UV radiation exposure. According to Conconi, “monitoring the formation of formazan in non-dividing yeast cells that are partially (rad7Δ) or totally (wt) proficient at DNA repair is a more accurate measure of cell survival after

Introduction Diet is a major lifestyle-related risk factor of a wide range of chronic diseases(15). Optimal eating is associated with increased life expectancy, dramatic reduction in lifetime risk of all chronic disease, and amelioration of gene expression(PMID: 24641555 ). It is known that an unhealthy diet can induce type 2 diabetes, obesity, Stroke, Cardiovascular disease, hypertension, inflammation, depression(Lucas et al, 2013), and micronutrients deficiency. On the other hand, a “ good ”

MD THESIS PROTOCOL A MORPHOLOGICAL STUDY OF THE DEVELOPING ENTERIC NERVOUS SYSTEM IN THE HUMAN FETAL COLON THESIS PROTOCOL SUBMITTED FOR THE DEGREE OF M.D. (ANATOMY) DR. DIVYA BARUHEE Junior Resident Department of Anatomy AIIMS, New Delhi MD THESIS PROTOCOL A MORPHOLOGICAL STUDY OF THE DEVELOPING ENTERIC NERVOUS SYSTEM IN THE HUMAN FETAL COLON Chief Guide DR. A. SHARIFF Professor Department of Anatomy AIIMS, New Delhi

Structure-based design and evaluation of synthetic porphyrin derivatives as G-quadruplex stabilizing anticancer agents R. N. Bhadanea*, D. B. Meshramb, R. M. Gilhotraa, R. R. BhadaneC aGyan Vihar School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, India bPioneer Pharmacy Degree College, Sayajipura, Ajwa-Nimeta Road, Vadodara, Gujarat, India cLoknete Dr. J. D. Pawar College of Pharmacy, Manur, Tal-Kalwan, Dist-Nashik, Maharashtra, India G-quadruplex structures formed in telomeres

As mentioned before, in tissue regeneration is of crucial importance the use of a 3D supportive structure because when cells are seeded into these scaffolds enables the proliferation of cells and chondrogenic differentiation; and with it the three-dimensional tissue formation. Scaffolds must be able to withstand physiological loading until sufficient tissue regeneration occurs. Moreover, the material must be sufficiently porous to allow for effective transport of nutrients. Finally, it should be

Since its first discovery in 1981, HIV/AIDS has killed more than 25 million people worldwide and is today the major threat to human health. However, due to the introduction of highly active antiretroviral therapy (HAART) as well as the impact of preventive measures, the prevalence and incidence of HIV have declined globally over the last decade except for parts of Eastern Europe and Central Asia where a slight increase has been observed (UNAIDS, 2010; Cohen, 2012; Futterman, 2012; Kumari and Singh