Genetic Diseases Essay

Sickle cell disease is a genetic disease that caused by abnormalities in the production of hemoglobin of red blood cells, characterized by its sickle-like shape. While the main function of hemoglobin in red blood cells is to carry oxygen to different parts of the body, these sickle cells are unable to perform this task adequately. The sickle shape of these red blood cells contributes to lower blood flow through vessels as they begin to build up and block passage through smaller blood vessels (“Facts

factors that seem to play a role in the development of Alzheimer’s disease. Human neurons are functioning cells of the nervous system that operate over an entire lifetime, yet the mechanisms that help preserve and protect against neurodegeneration during aging are unknown. There are fundamental questions as to why some individuals age with their cognitive functions relatively intact and others who decline and develop Alzheimer’s disease. Scientist have made it clear that neuronal cell numbers is preserved

Alzheimer's disease(AD), accounts for approximately 70% of cases of dementia. As this disease progresses, symptoms include problems with language, disorientation, mood swings,hallucinations, depression, difficulty with self-care, and behavioral issues. Alzheimer's, causes brain cells to degenerate and die, with this results in the destruction of memory and the ability to perform simple tasks. However as the progression can vary, the average life expectancy is eight to 10 years after diagnosis.

Tay Sachs Disease is an inherited disorder that kills nerve cells in the brain, and also in the spinal cord. A couple of things that could cause this mutation is a missing enzyme. This is an enzyme called ganglioside, that is a fatty substance. Another reason why tay sachs could appear is a change in chromosomes. This is chromosome number 15. The gene is the HEXA gene, or hexosaminidase A. This is a recessive disorder that you can only inherit if both parents have tay sachs. Some symptoms to know

Abstract: Huntington’s Disease- Huntington 's disease (HD) is a neurodegenerative genetic disorder. It affects the muscle coordination and decline in cognitive that leads to dementia. It affects both males and females in their middle age (J.D, 2015). Huntington’s disease is most common in genetic causes the leads to abnormal involuntary movement also called Huntington’s chorea (J.D, 2015). Epidemiology: Huntington 's disease is a rare neuropsychiatric disorder it occurs in a

Sickle cell disease (SCD) is a genetic, autosomal recessive disorder that is caused by mutations in the β-globulin gene. “The term sickle cell disease (SCD) describes a group of inherited red blood cell disorders. People with SCD have abnormal hemoglobin, called hemoglobin S or sicklehemoglobin, in their red blood cells.” (What Is Sickle Cell Disease? - NHLBI, NIH, n.d.). The disease is inherited whereas the recessive gene is passed by each parent to child. If only one gene is passed, they are considered

organism is due to genetic cellular and molecular modifications. The level of changes on the longevity of the plant can affect it in several ways in a gradual process as the age progresses with time. According to Finch, the process of aging can also have a definition that it is the accumulation of underlying molecular errors (Finch,2007). These errors with time eventually corrupt the adult stem cells. The effect of the accumulating errors is due to some epigenetic and genetic interactions (Finch

Genetic diseases are passed down through parents and genes. I have an aunt name Katie who has an inherited disease, which she has been living with for sixteen years called TS. Tourette syndrome is one of the most common genetic diseases. Although you never too much here of any one with this disease or do many take it serious, TS is a very serious disorder. Tourette Syndrome is an inherited nervous system disease causing constant movement & unwanted sounds. There has not been any cause of TS, but

Parkinson’s disease is the second most common neurodegenerative disease known to humans, characterized by loss of control of the central nervous system, and has been studied extensively by the scientific community (Hering et al. 2004). One gene loci identified as PARK7 or DJ-1, has been mapped to chromosome 1p36 and contains the DJ-1 protein (Bonifati et al. 2003). Mutations on the DJ-1 gene are shown to reduce the function of this gene, subsequently leading to the early onset Parkinson’s disease (Bonifati

chromosome 14 that is linked with Alzheimer’s disease, which was shown to be an autosomal dominant trait (Schellenberg et al., 1992). Figure 3 illustrates the map of the chromosome 14 markers. D14S43 was found to be a strongly positive marker in chromosome 14 for EOAD (Schellenberg et al., 1992). This illustrates that, although chromosome 21 if often the main focus of AD researchers, chromosome 14 also plays a large role in the development of the disease. In summary, chromosome 21 holds the loci responsible