Genomics

Genomics in rapid-response diagnostics Currently, the gold-standard assay for cholera diagnosis is the isolation and identification of V. cholera from cultured stool samples. This culture-based method may take up to 48 hours for results and relies on clinical symptoms and prior knowledge for pathogen identification. This method remains problematic for developing successful control strategies, particularly for the current asymptomatic El Tor strain 7P. To complicate matters further, V. cholerae cannot

coursework has grown every year; however, the opportunity to discover novel information through my research is one of the most intellectually stimulating experiences. Under the guidance of Dr. Nolan Kane, the Professional Investigator of the Cannabis Genomic Research Initiative (CGRI), I have expanded from traditional bench work to bioinformatics, hemp breeding, and leading and designing my own project analyzing differential RNA expression in Cannabis. Through my work and fascination with this four nucleotide

coursework has grown every year; however, the opportunity to discover novel information through my research is one of my most intellectually stimulating experiences. Under the guidance of Dr. Nolan Kane, the Professional Investigator of the Cannabis Genomic Research Initiative (CGRI), I have expanded my traditional wet lab work to bioinformatics, hemp breeding, and leading a project I designed to analyze differential RNA expression in Cannabis. Through my work and fascination with this four nucleotide

In the past two decades, technological advances in the biomedical and genomic fields have generated enormous volumes of -omics data. These data continue to be scattered in various databases accessible through the World Wide Web (Table 1), there have been some significant efforts to integrate these to answer specific questions (e.g., candidate disease gene prioritization1, tissue-specific interaction networks2, etc.). Concomitant with the development of specialized powerful gene and protein and disease

Genetic and Genomic Education and Practice in Nursing The Human Genome Project launched in 1990 and marked the start of an evolutionary change in healthcare. Medicine has made great advancements following the completion of the Human Genome Project (HGP) in 2003. In addition to these advancements, the scope of practice for nurses’ is continuously changing and expanding. There is a growing emphasis on genetic literacy in the nursing profession. In the era of personalized medicine, registered nurses

Other methodologies for integrative genomic analysis in cancer have been studied previously. The review presented in \cite{kristensen2014principles} summarizes a number of different tools and algorithms used in this area. The paper classifies these methods into statistical, machine learning, gene set, network, and other analysis techniques.\\ Many work has been done to perform an integrated analysis using genetic and gene expression data. In \cite{xiong2012integrating}, the authors illustrated

INTRODUCTION Regulatory factor is bound with genomic DNA to protect the sequence from cleavage through DNase I. With the help of DNase I, it is easy to identify the 41 diverse cells with nucleotide resolution. Around 45 million transcription factors are detected in the regulatory regions. They represent the binding to the elements that are of short sequence. Genetic variations affect the allelic chromatin which is present in concentrated manner in the footprints. But these variations effects are

Article 1. Gallant, Jason R. et al. 2014. Genomic basis for the convergent evolution of electric organs. Science 344 (6191) :1522-1525. • (Ho)- The electric organs are a characteristic in electric fishes that have changed separately numerous times over generations and are used to make electricity to navigate, to communicate, to help in defense and to aid in catching and eating prey but have no similarities between the lineages. • (Ha)- The electric organs are a characteristic in electric fishes

Precise genomic-based classification of cancer subtypes Motivation Cancer diseases are a collection of heterogeneous disease entities, which differ substantially in clinical outcomes and risks with respect to genetic factors, environmental factors, and clinical characteristics such as age, gender, etc. Certain therapy can benefit one subgroup in survival, but maybe ineffective for another subgroup. Subtype-specific diagnostic and prognostic tools can help physicians to predict the efficacy of

The first part of the experiment was to isolate the human genomic DNA from cheek cells. The cheek swabbed and cut off the end and inserted it into a microfuge tube. 500 μL of PBS was added to the tube. Then, the tube was shacked and the swab removed then centrifuged for 1 minute at 8,000 RPM. After it was centrifuged, a supernatant was formed with was removed. 300 μL of ACL solution was added to the pellet as well as 20 μL of protease stock solution. This was incubated at 50 ˚C and the temperature