Glutathione

p. 71). As the glutathione conjugation (phase II) plays main role in metabolism of anticancer compound, this point will be focused on. Glutathione are one of the major mechanisms controlling cellular oxidative balance (Pei et al 2013, p.2). There are three main function of glutathione (GSH) according to Pei et al (2013, p.2) : The role of glutathione can be explained by using example of human acute myelogenous leukemia (AML) cells. By targeting the glutathione pathway, this cancer cell

Research question: Does dietary intake of milk and milk products stave off cognitive decline and dementia in older adults? Thesis: It is predicted that regular dietary intake of milk and/or milk products can reduce the effects of cognitive decline and dementia and/or improve cognition in older adults compared with irregular or nonexistent milk/milk product intake. Introduction: a. Cognitive decline in older adults, and its impact i. Cognitive decline, particularly dementia, remains among the most

Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore. “ESTIMATION OF PLASMA AND SALIVARY ANTIOXIDANTS IN PATIENT WITH RECURRENT APHTHOUS STOMATITIS” By Dr. SACHIN GANESAN. Dissertation Submitted to the Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore. In partial fulfillment of the requirements for the degree of MASTER OF DENTAL SURGERY IN DEPARTMENT OF ORAL MEDICINE AND RADIOLOGY Under the guidance of Dr. SHAMBULINGAPPA P., M.D.S. PROFESSOR DEPARTMENT OF ORAL MEDICINE

allotted to a 2 [Low (14-16℃) or control temperature] × 2 (0.17% or 0.51% DL-HMTBA) factorial arrangement to investigate effects of DL-HMTBA on the gene expression related to oxidative stress in low temperature. The hepatic glutathione (GSH), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities were decreased, while protein carbonyl and malodndialdehyde content in lung were increased in low temperature (P10-fold decrease in CβS protein levels. Therefore, it indicated that DL-HMTBA

Mechanism of how antioxidants can preserve stem cell function: LUO2014 * Effects of antioxidants induced pluripotent stem cells: They tested whether the addition of low-dose antioxidants influences the growth, quality, and genomic stability of induced pluripotent Stem cells (iPS cells). They found that the iPS cells grew well and ‘‘stemness’’ was preserved up to 2 months with the addition of low-dose antioxidant. However, the addition of low-dose antioxidants lowered the intracellular reactive oxygen

G6PD deficiency is an inherited condition in which the body doesn't have enough of the enzyme glucose-6-phosphate dehydrogenase, or G6PD, which helps red blood cells (RBCs) function normally. This deficiency can cause hemolytic anemia, usually after exposure to certain medications, foods, or even infections. Most people with G6PD deficiency don't have any symptoms, while others develop symptoms of anemia only after RBCs have been destroyed, a condition called hemolysis. In these cases, the symptoms

irradiation plus spermine, lead plus spermine, irradiation plus lead co-treated with spermine) for consecutive 14 days. Complete blood count (CBC) and blood glucose-6-P-dehydrogenase (G6PD) were measured in blood. Moreover, malondialdhyde (MDA), glutathione (GSH), metallothionin (MT) levels and catalase (CAT) activity were investigated in liver, kidney and brain. G6PD significantly decreased post exposure to lead and /or gamma irradiation. Hepatic, renal and brain MDA, GSH, MT and CAT were significantly

Heavy metal poisoning is nothing new. It has been known for centuries that some heavy metal compounds are quite toxic to people. A particularly infamous and widely known heavy metal is lead. Lead has been a particular useful element in early human history. It saw many uses from making jewelry to the height of its use in the ancient world as Roman plumbing. Most people would shudder at the thought of drinking water from lead pipes with all the hysteria associated with lead; however, lead pipes or

Antioxidant and Anti-inflammatory Properties of Lunasin: Experimental, clinical and epidemiological studies have revealed that chronic inflammation is involved in the development of approximately 15–20% of malignancies worldwide52, being clearly associated with increased risk of cancer and cancer progression53. It is believed that persistent inflammatory cells recruitment, repeated generation of reactive oxygen species (ROS), pro-inflammatory mediators and continued proliferation of genomically

For centuries, pesticides have been used in agriculture to increase the production of high-quality crops by controlling diseases' vectors. Recently, they are increasingly used worldwide but its severity is much pronounced in the third world countries. Among commonly used pesticides, organochlorine and pyrethroids are used in agriculture, medicine, and industrial fields. The extensive application of pesticides has a negative effect on the environment particularly water. Owning to overspray and drain