Graft-versus-host disease

Sort By:
Page 4 of 12 - About 111 essays
  • Decent Essays

    The controversy of stem cell therapy is mainly dependent on whether its advantages outweigh the disadvantages, its plasticity and degree of differentiation, availability are also of great deal to carrying out stem cell transplantation (Habib and Gordon, 2006).One of the advantages of adult stem cells is that they can be found in a number of tissues and organs in the body, and can be acquired using a variety of techniques depending of which type of stem cells are needed to be collected (Habib and

    • 455 Words
    • 2 Pages
    Decent Essays
  • Decent Essays

    “Bubble Boy Disease” When putting the “Bubble Boy Disease” in the past, gene therapy can be the time machine to send it back. Gene therapy can help replace infected cells in a patient’s body with healthy, new cells. SCID is a severe disease that can be greatly impacted by gene therapy. New advancements are being made and a gene therapy method can be used to transfer bone marrow into the patient, instead of transferring the cells. The future of gene therapy can help cure SCID. Severe Combine Immunodeficiency(SCID)

    • 662 Words
    • 3 Pages
    Decent Essays
  • Decent Essays

    Aplastic Anemia - Essay

    • 836 Words
    • 4 Pages

    The multipotent stem cells in the bone marrow reconstitute all three blood cell lines, giving the patient a new immune system, red blood cells, and platelets. However, besides the risk of graft failure, there is also a risk that the newly created white blood cells may attack the rest of the body ("graft-versus-host disease"). Medical therapy of aplastic anemia often includes a short course of anti-thymocyte globulin (ATG) or anti-lymphocyte globulin (ALG) and several months of treatment with ciclosporin to

    • 836 Words
    • 4 Pages
    Decent Essays
  • Decent Essays

    Sickle Cell Anemia (SCA)

    • 592 Words
    • 3 Pages

    101: Sickle Cell Anemia Sickle cell anemia (SCA) is a widespread disorder of hemoglobin synthesis, sometimes termed a hemoglobinopathy. As with other hemoglobinopathies, SCA is an autosomal recessive disease, meaning a person must have two defective genes present for the full blown disease to occur. People who carry a single sickle cell gene are said to have sickle cell trait. The children of two carriers have a 25% chance of inheriting SCA. Epidemiology In the U.S., SCA occurs most often

    • 592 Words
    • 3 Pages
    Decent Essays
  • Decent Essays

    stem cells, since they are from the own individuals body, are not put at risk to be rejected or attacked by the body by presenting itself as a foreign body. Allogenic stem cells, since they are coming from a donor’s body are at risk of rejection and Graft

    • 477 Words
    • 2 Pages
    Decent Essays
  • Decent Essays

    Kir Essay

    • 887 Words
    • 4 Pages

    suppression of autologous NK cells, many groups have evaluated adoptive immunotherapy utilizing donor derived allogeneic NK cells. . The importance of NK cells in alloHSCT can be characterized by their role in mediating immune reconstitution, GVHD, disease relapse, and infection control22. As such, the importance of NK cells is underscored by the fact that they are the first

    • 887 Words
    • 4 Pages
    Decent Essays
  • Decent Essays

    aware. HIV is a virus that integrates its viral DNA into host cells, a necessity for its survival. By taking advantage of the natural genetic mutation in CCR5-delta, that occurs in some individuals making them immune to the disease, we hope to replicate this in the form of a potential treatment. In 2016, 1 million people died of the later form of the disease known as AIDS. This is a huge public health issue, and with yet no cure for the disease, its discovery is in high demand. The importance of finding

    • 1318 Words
    • 6 Pages
    Decent Essays
  • Decent Essays

    According to the National Marrow Donor Program, stem cell therapy in the form of a bone marrow transplant is used for patients suffering from multiple sclerosis, leukemia, and lymphoma. Stem cells are important for patients who are suffering from diseases without a cure. The stem cell treatment allows the cells that have died to be replaced which in terms prolongs the patient’s life. Stem cell treatment is also used in knee injuries. However, there are many complications with stem cell transplants

    • 1127 Words
    • 5 Pages
    Decent Essays
  • Decent Essays

    NK Cells Case Study

    • 1232 Words
    • 5 Pages

    a transplant after the original publication. 33 All patients evaluated received a myeloablative T cell depleted haploidentical transplant 33. Alloreactions in the graft versus host direction were identified in 51 patients 33. In contrast to the initial study, transplantation from alloreactive NK cells did not significantly reduce graft rejection or incidence of GVHD. Despite no increased protection from GVHD, there was a marked improvement in

    • 1232 Words
    • 5 Pages
    Decent Essays
  • Decent Essays

    SCD is genetic mutation that is caused by a genetic point mutation where a single nucleotide base has been substituted by an incorrect base (also termed transversion). The transversion caused by the SCD will alter the codon, at the 17th nucleotide of the beta chain of hemoglobin molecule it would be incorrect; thus, when the mRNA carries the gene which codes for Hb molecule, at the 17th nucleotide the ribosome will start synthesizing a different amino acid. At the site of the Hb molecule its adenosine

    • 809 Words
    • 4 Pages
    Decent Essays