Graft-versus-host disease

leukemia may choose watchful waiting—an option that involves not getting treated right away, but instead waiting until the treatment is needed. Chronic leukemia is rarely cured with chemotherapy, but stem cell transplants offer hope in curing the disease. Stem cells are cells whose roles in the body have yet to be determined. They have the potential to differentiate into specialized cells, and every type cell in the body forms from stem cells. This ability to differentiate into other cells is what

Blood transfusions can be defined as medical procedures that is used by medical professionals and often saves lives. During a blood transfusion, a health professional transfers donated blood to an affected patient’s body. Blood transfusions have made it possible for many individuals to be alive. These medical procedures have impacted the field of medicine in both a positive and a negative manner. Blood transfusions have benefited the world because they have made many medical procedures be possible

Blood transfusion has been performed for centuries after the three blood types were discovered. However, only in 1907 the first fairly safe blood transfusion happened after the fourth type of blood was discovered by Dr. Reuben Ottenberg of Mount Sinai Hospital in New York. Researcher in Brussels and Bueno Aires found that Sodium Citrate prevents blood clotting (Levy, 2015), which made possible to store blood for future transfusions. In 1941 the American Red Cross established the blood donor service

Bipolar disorder is a complex mental health disorder that is characterized by recurrent episodes of elevated or irritable mood with variable states of depression (American Psychiatric Association, 2013). Patients suffering from bipolar disorder not taking any maintenance medications have been shown to have relapse rates of approximately 61%, leading to significant impairments in functioning and quality of life (Goodwin et al., 2004). Anticonvulsants used as mood stabilizers have become the main therapy

program, I was granted an opportunity to work as a resident in the Europe’s second largest bone marrow transplant unit at Saint-Louis Hospital, Paris. I participated in a study that evaluated the NIH classification of acute and chronic graft-versus-host disease in reduced intensity conditioning transplantation. As me being the first author, the research was presented at the poster session of

Page 1 Use of stem cell research Page 3 Diseases stem cell research has contributed positively to thus far Page 4 Possibilities stem cell research as provided Conclusion Introduction Stem cells have the potential to develop into various

INTRODUCTION CD8+TCR- facilitating cells (FC) derived from bone marrow (BM) enhance engraftment of purified hematopoietic stem cells (HSC) in allogeneic mouse recipients without causing graft-versus-host disease (GVHD).1 The major subpopulation of FC resembles plasmacytoid precursor dendritic cells (p-preDC) both phenotypically and functionally.2 Transplantation of FC results in increased expression of transforming growth factor-β (TGF-β) and the induction of the regulatory T cell (Treg) associated

This results in a massive influx of leukocytes especially neutrophils to the site of infection. S. aureus produces haemolysins and leukocidins that are able to lyse host blood cells. When leukocytes, especially neutrophils, are lysed, they release lysosomal enzymes that damage the surrounding tissue. The host response to this tissue damage is to deposit a fibrin capsule around the damage containing it to the site of the infection. This fibrin capsule also protects the bacteria inside

minutes. Of the blood cancers, leukemia accounts for 33% of the deaths (Siegel, Naishadham, & Jemal, 2013). Because the cancer stems from a transformation from healthy hematopoietic stem cells to leukemic stem cells, it would be beneficial to treat the disease with a stem cell therapy. The purpose of this study is to understand the mechanism of how hematopoietic stem cells are turned into leukemia stem cells and be able to prevent the transformation. It will be another step for researchers to find a less

Side effects of cancer treatments Cancer, a group of disease which are a menace to the world at the moment usually is doted as a sword of death and which everyone tries to avoid getting face to face with in their lifetimes. Even with the advancement in the medical research which is effective enough to tackle and cure cancer in the initial stages, the treatments offered to the cancer patients are usually laden with an array of side effects which pose to be a problem in the later days to come. Here