Human respiratory syncytial virus

DETAILS Name: Teija FRAME Student Number: 43132289 Proposal Title: Plasmacytoid dendritic cells promote host defense against viral-induced asthma pathology via IRF7 expression ABSTRACT/ SYNOPSIS (250 WORDS MAXIMUM) Asthma is a chronic inflammatory respiratory disease characterized by airflow obstruction, airway hyper-responsiveness (AHR) and expression of CD4+ T cell mediators. Infant viral infection has been shown to be the greatest risk factor for developing asthma later in life. Production of type

Virus and Bacteria Virus - A virus is a capsule of protein that contains genetic material. A virus cannot reproduce on its own; it must infect a living cell to grow. Bacteria - Bacteria are one-celled organisms that live on their own. They can multiply and reproduce by subdivision Bacteria and viruses cause many of the diseases we are familiar with and may sound synonymous; they are greatly different from each other. [pic] o They differ greatly in size. The biggest viruses are only as large

upper respiratory tract. Children under six years are infected quite frequently, and experience such colds approximately 6-8 times per year, with symptoms lasting up to 14 days. Symptoms may include congestion, rhinorrhea, sneezing, cough, headache, slight fever, and malaise. Rhinoviruses are responsible for 30-50 percent of the URIs in children and are present year round, peaking in September, March, and April. Other viruses accounting for URIs in children include respiratory syncytial virus

infected child. This is a very contagious disease that usually consists of a rash, fever, and cough. The rubeola virus can live on surfaces for hours. The virus was first isolated in 1954 by Nobel Laureate John F. Enders and Thomas Peebles, who were careful to point out that the isolations were made from patients who had Koplik 's spots, white spots under the tongue. The rubeola virus

Epidemiology: RSV plays a major role in respiratory infection among the childhood population, especially infants and younger children. It is the leading viral agent respiratory tract disease worldwide, causing bronchiolitis and pneumonia in infants and young children. There are about 100,000 cases and 4,500 deaths yearly of RSV infections in the United States (1). Typically, all children are infected with RSV by age 2 to 3; however, the infections can reemerge up to 5 to 6 per year. RSV was first

capsid structure (Doerfler 1996). The virus particle has spikes on the base of each capsomer that aid in attachment to the host cell. At the core of the virus is double-stranded linear DNA that replicates in the nucleus of the host cell. Adenovirus infection is a communicable disease and transmission of the adenovirus particle occurs in two general ways. The virus can be spread in airborne droplets that are released when an infected person sneezes or coughs. The virus can also be transmitted by contact

diffuse, inflammatory obstruction in the small airways or bronchioles occurring most commonly in children” (Heuther & McCance, 2012). It is an acute inflammatory disease of the lower respiratory tract that occurs most commonly in infants and is caused by infection with seasonal viruses such as respiratory synctial virus (RSV) (Zorc & Hall, 2010). Bronchiolitis often results from an obstruction of the small airways. It is the leading cause of infant hospitalization in the United States (Zorc & Hall

Plasmacytoid dendritic cells promote host defense against viral-induced asthma via IRF7 activation ABSTRACT/ SYNOPSIS (250 WORDS MAXIMUM) Asthma is a common respiratory disorder that is mediated by T helper type 2 (TH2) cytokine production, leading to airflow obstruction and airway hyper-responsiveness. Infant infection of human respiratory syncytial virus (RSV) has been shown to be the greatest risk factor for developing asthma. Interferon regulatory factor 7 (IRF7), activated by TLR7 in pDCs, is a crucial

Paget, an English surgeon, who first described the disease in 1877. Since then, research has determined that 15% to 40% of cases are inherited and the balance is thought to be caused by exposure to a “slow” viruses like human respiratory syncytial virus or canine distemper virus, however, symptoms may not appear for many years afterward. In about half of cases that are hereditary, a mutated gene has been isolated that is known to cause osteoclasts to become rogue and un-regulated. PDB causes long

varicella-zoster virus. Signs and symptoms of chickenpox may include: Slight fever may be present before a rash develops. Rash usually first appears on body, face, and scalp. It then spreads to limbs. Rash begins as small, red, flat spots that develop into itchy fluid-filled blisters. Blisters are usually less than ¼” wide and have a red base. After the blister breaks, open sores will crust over to form dry, brown scabs. (BCCDC, 2009) Treatment: “Most healthy children and adults