Immunofluorescence

Non-healing Skin Lesion With a plethora of skin lesion etiologies, a thorough focused history and physical examination is essential for recognition and its diagnosis (Dains et al., 2016, p. 325). In the case of John and his children, the onset of the lesion as well as his exposure to the outdoors are considered in the differential diagnoses. Additionally, both the positives and the negatives were taken into consideration when noting his history, in the review of systems, and in the physical examination

Abstract Relapsing polychondritis is thought to be a rare auto immune disease. While reading articles and research I found that those with relapsing polychondritis had antibodies against type II collagen and in increase in HLA-DR4 antigen which gives insight to the etiology of the disease. An abundance of research is done by case studies and mouse/rat models. A patient has increased erythrocyte sedimentation rate and C reactive protein as well as leukocyctosis, thrombocytosis, chronic anemia, and

Malaria is spread to people by the female Anopheles mosquito. Only Anopheles mosquitoes can transmit malaria. These mosquitos must have been infected through previous blood taken from an infected person. When a mosquito bites an infected person, a small amount of blood is taken and contains microscopic malaria parasites. (CDC, 2015) When the mosquito takes its next blood meal from another person a week later, the parasites will be injected. The malaria parasite is found in red blood cells of an infected

pathogensis of ALS. TDP-43 was first identified in 2006 [Neumann, Sampathu and Kwong, et al., 2006] where it was shown there was a link between the protein and both ALS and frontotemperal lobar degeneration (FTLD). This study used double-labelling immunofluorescence to show that TDP-43 antibodies (antiTDP-43) immunolabelled ubiquitinated cytoplasmic, nuclear, and neuritic inclusions in sALS. However, it remained unclear how and what gene mutations were the underlying cause. This study observed that patients

This article is about how to detect circulating tumor cells using negative enrichment immunofluorescence and an in situ hybridization system in pancreatic cancer. Pancreatic cancer is known as the most lethal malignancy with an extremely 5-year survival rate. Circulating tumor cells are the tumor cells that fall off from solid tumor masses and travel into the peripheral blood circulation, and they have been popularly detected by the CellSearch system and used as promising biomarkers to monitor chemotherapeutic

ADVANCES IN MICROBAL ANALYSIS OF WATER-A REVIEW ABSTRACT Microbes are known to cause a wide variety of diseases. The Microbial pathogens are one of the major health gamble associated with water and wastewaters. Traditional methods of the detection of pathogenic organisms tend to be error prone, time consuming and expensive. Indicator bacteria are commonly used to determine the relative risk of contaminants in water. Indicator organisms, however, have several problems for it to be an ideal and reliable

leaking into the urine (National Institute of Diabetes and Digestive and Kidney Diseases, 2010). Pauci-immune glomerulonephritis is the primary type of rapidly progressing glomerulonephritis. It refers to the lack of immune deposits witnessed via immunofluorescence. Necrotizing glomerular inflammation is a key histological component of this disease (Moreland, 2004). Crescentic

Morphologic changes of the cells infected with rubella virus cannot be observed easily. Estimation of the size of the cultured cells can be a valuable parameter in this condition. Therefore, detection of morphological changes of the cells or nuclei induced by the virus before observing any later marked changes can be beneficial. Briefly, the study was conducted to find answers to the following questions. How much time after infecting with rubella virus the volume and surface area of the Vero cells

As mentioned before, in tissue regeneration is of crucial importance the use of a 3D supportive structure because when cells are seeded into these scaffolds enables the proliferation of cells and chondrogenic differentiation; and with it the three-dimensional tissue formation. Scaffolds must be able to withstand physiological loading until sufficient tissue regeneration occurs. Moreover, the material must be sufficiently porous to allow for effective transport of nutrients. Finally, it should be

Diabetes is a worldwide public health problem that has being drastically increased in the last years. It is classified as the second most common disease affecting humanity (), regardless of socioeconomic status, religious and geographical location. Diabetes is projected to be the world’s main killer in next few years, mainly because of the complications that it causes in other organs and systems. For the last decades, several researches are being conducting in order to have a better understand of