Junction

The exon junction complex (EJC) is a well-known RBP: an RNP complex consists of at least four core proteins (eIF4AIII, BTZ, MAGOH, and RBM8a). EJC factors labels the exon junctions of mRNA and plays critical roles in mRNA splicing, export and degradation. Recent studies revealed that recessive mutations of RBM8a cause thrombocytopenia-absent-radius

The neuromuscular junction constitutes of three regions consisting of the presynaptic cell, the synaptic cleft, and the post synaptic cell. The presynaptic cell is responsible for sending the incoming potential from the axon terminal, to the target cell. This is done by action potentials arriving tot the axon terminal. As a result, voltage gated Ca2+ channels are opened, allowing Ca2+ to enter the cell. Ca2+ will then bind to the synaptotagmin on the vesicles, enabling the vesicles to move through

A neuromuscular junction is a chemical conjunction formed during the contact between motor neuron and a muscle fiber. Each branch of a motoneuron forms a single junction with a muscle fiber (University of Minnesota, 2011). At the neuromuscular junction, the motor neuron is able to send a signal to the muscle fiber which ultimately allows for muscle contraction. The operation, when the neurotransmitter, are released by a neuron begins when the action potential reaches the presynaptic terminal of the

the space located between the motor neuron and the skeletal muscle which is also referred to as a neuromuscular junction. The motor neurons that originate from the spinal cord, help activate the skeletal muscle fibers. The innervation happens by the processes of the axon. The synapses are present along with these processes and are also known as motor endplate. The neuromuscular junction synapse has three characteristics. It consists of two membranes called the pre and post synaptic membranes and the

Without the neuromuscular junction, and the action performed by exocytosis, the body simply cannot move. The neuromuscular junction (NMJ) is a specialized synapse that is responsible for commuting between the motor neuron and the muscle fiber by transmitting signals. The process of exocytosis is important as it involves the use of vesicles fusing with the plasma membrane and secreting its contents into the extracellular space. The NMJ has been extensively studied to understand its process of synaptic

Tight Junction Function Response to Unknown Bacterium in Intestinal Epithelium Introduction Tight junctions function as barriers in epithelial cells through the formation of protein complexes between neighboring cells. Made up of three transmembrane protein families including the occludin proteins, the claudin proteins, and the junctional adhesion molecules (JAMs), tight junctions are able to maintain the distinction between the apical and basolateral regions of the cell as well as maintain the

Apache junction is a complex diverse community with its own unique landscape. Apache Junction has its own unique problems and challenges just like any community. Apache Junction is a relatively small city compared to the other cities that make up the Phoenix metropolitan area with a population of about 38,000 people, with a land area of about 35 square miles (United States Census Website, 2013). Exploring what makes up the social determinates, economic determinates, environmental determinates, and

there are many services and many sources that people must consider carefully. Our community, Junction City, is suitable for using these impacts as huge benefits. Through the Sunflower Bank Program, I had a lot of opportunities to learn about the process of economic development, major basic sources for a good economy, and reasons that why Junction City is a good place for starting a business. First of all, Junction City has a population and various opportunities for education. Fort Riley, one of the largest

Abstract Summary Gap junctions are large channels which join two adjacent cells connecting their cytoplasm’s allowing direct cell to cell communication and interactions by the channeling of molecules. A gap junction is composed of two hemichannels known as connexions, one located on the membrane of each of the adjacent interacting cells. The binding of six connexin subunits is required for the formation of each of the connexion hemichannels which then join together via hydrophobic interactions forming

Battle of Layac Junction December 7, 1941, Japanese air and naval forces struck multiple areas within the Pacific to include Kota Bharu in British Malaya, Singora in Thailand, Guam, Hong Kong, and the Philippine Islands. One of the prominent attacks targeted Pearl Harbor, marking the United States declaration of war against Japan, in which the United States entered World War II. The capture of the Philippine Islands served as a crucial effort to the Empire of Japan in ensuring the control of the