Lupus Nephritis Lupus nephritis causes inflammation of the nephrons, which is caused by systemic lupus erythematosus (SLE or lupus). The kidney’s main function is to remove waste from blood and to balance the amount of fluids in your body. When inflammation of nephrons occur it makes it harder to filter the blood and can cause significant swelling. It is an autoimmune disease that causes the immune system to mistake harmful substances from healthy ones which results in the immune system attacking
activity indices have been formulated, including the SLEDAI (Systemic Lupus Erythematosus Disease Activity Index), SLAM (Systemic Lupus Activity Measure), BILAG (British Isles Lupus Assessment Group) (Ben-Menachem, 2011). Assessing Chronic Damage of SLE: In 1996, a damage index for SLE was developed by the SLICC and endorsed by the ACR; hence, it has become known as the SLICC/ACR Damage Index which complements other measures of lupus disease activity as an outcome measure (Gladman et al., 1996). There
LUPUS An autoimmune disease that causes the body to attack its own healthy cells, lupus has no known origin. While its symptoms are primarily recognizable, they can often mimic other diseases, thereby delaying accurate diagnosis. Joint pain, poor circulation and a telltale rash are just three of myriad symptoms indicative of lupus, a disease that inevitably impacts major organs by way of compromising the body's defenses, as well as through invasive steroid treatment that weakens bones. Lupus
Lupus Case Study Overview There are several types of lupus, but the most common and severe type is called Systematic Lupus Erythematosus or SLE. This form of lupus is an autoimmune disease that causes a chronic inflammation that can affect many major organs in the body. Common areas of the body that are affected are the skin, joints, kidneys, lungs, heart, and the nervous system. The immune system is the part of the body that fights off viruses, bacteria, and germs, and other foreign substances
Lupus is a chronic inflammatory disease that occurs when your body’s immune system attacks your own tissues and organs. The inflammation caused by lupus can affect many body systems including the following: joints, skin, kidneys, blood cells, heart and lungs. Lupus occurs more frequently in women than in men. There are four different types of Lupus that exist. They are Systemic lupus erythematosus, Discoid lupus erythematosus, Drug-induced erythematosus, and Neonatal lupus. The most common and
Zagazig University Faculty of Medicine Clinical Pathology Department Association of STAT4 Gene Single-nucleotide Polymorphism with Systemic Lupus Erythematosus Thesis Submitted for partial fulfillment of M.D. degree in clinical pathology By Marwa Abd El-Monem Mohamed Ateya MB.B.CH. Ass .lecturer of Clinical Pathology Faculty of Medicine Zagazig University Prof. Dr. Lamiaa Abd Al-wahab Mohammad Professor of Clinical Pathology Faculty of Medicine Zagazig University Prof. Dr. Asmaa
In Partial Fulfillment of the Requirements in NCM 105 A Case Study on Systemic Lupus Erythematosus December 2010 Table of Contents Acknowledgement…………………….. 3 Objective………………………………. 4 Scope and Limitations............................. 5 Introduction…………………………….. 6 Review of Related Literature…………… 7-8 Case Analysis…………………………… 9 Health History………………………….. 10 Family Genogram………………………. 11 Anatomy and Physiology………………. 12-13 Pathophysiology………………………… 14-17 Nursing Assessment Tool……………….
This is a longitudinal cross sectional study of all children and adolescents patients with LN following inPediatric Allergy and Immunology clinic, Children 's Hospital, Ain Shams University in the period between October 2013 and February 2014. Lupus nephritis in patients with pediatric onset SLE was diagnosed and graded on pathological basis according to 2003 ISN/RPS classification of LN into Class I: Minimal mesangial LN. Class II : Mesangial proliferative LN. Class III: Focal LN (≤50% of glomeruli)
Systemic Lupus Erythematosus What is Systemic Lupus Erythematosus? Systemic Lupus Erythematosus – otherwise known as lupus – is an inflammatory autoimmune condition and typically affects women of reproductive age and causes joint pain. Other manifestations of the disease include fatigue, rash, dry eyes/mouth, inflammation in other parts of the body, and blood cell abnormalities. One of the most worrisome complications of lupus is kidney disease, which is a common cause of dialysis dependence in
narrowing the gap between the observed effects of placebo treatment and that of a potentially useful medication. The SLEDAI also doesn 't account for subjective symptoms like fatigue, dysphoria, arthralgia or myalgia, which might genuinely reflect lupus activity, and may be of high importance to patients (Fortin et al. 2000; E. Chang et al. 2002). An update version SLEDAI-2000 (SLEDAI-2k) was introduced and validated in 2002 based on findings in the preceding 10 days. SLEDAI-2k allow the documentation