Lupus nephritis

Lupus is a chronic, autoimmune disease that can damage any part of the body like your skin, joints, and, or organs. When someone has lupus, something goes wrong with their immune system. Because it is an autoimmune disease, the immune system cannot tell the difference between the foreign invaders, like the flu, and the body’s healthy tissues. So it creates autoantibodies that attack and destroy the healthy tissue, which causes inflammation, pain and damage in various parts of the body. It is also

Lupus is a chronic inflammatory disease that occurs when your body’s immune system attacks your own tissues and organs. The inflammation caused by lupus can affect many body systems including the following: joints, skin, kidneys, blood cells, heart and lungs. Lupus occurs more frequently in women than in men. There are four different types of Lupus that exist. They are Systemic lupus erythematosus, Discoid lupus erythematosus, Drug-induced erythematosus, and Neonatal lupus. The most common and

Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease that occurs when a person’s immune system attacks your own tissues and organs. SLE is characterized by the presence of autoantibodies directed against nuclear antigens. By definition, SLE is a multi-system disease, and patients can be infected in vastly different ways. SLE is the form of the disease that most people are referring to when they say “lupus.” The word “systemic” means the disease can affect not one, but many parts of

Zagazig University Faculty of Medicine Clinical Pathology Department Association of STAT4 Gene Single-nucleotide Polymorphism with Systemic Lupus Erythematosus Thesis Submitted for partial fulfillment of M.D. degree in clinical pathology By Marwa Abd El-Monem Mohamed Ateya MB.B.CH. Ass .lecturer of Clinical Pathology Faculty of Medicine Zagazig University Prof. Dr. Lamiaa Abd Al-wahab Mohammad Professor of Clinical Pathology Faculty of Medicine Zagazig University Prof. Dr. Asmaa

In Partial Fulfillment of the Requirements in NCM 105 A Case Study on Systemic Lupus Erythematosus December 2010 Table of Contents Acknowledgement…………………….. 3 Objective………………………………. 4 Scope and Limitations............................. 5 Introduction…………………………….. 6 Review of Related Literature…………… 7-8 Case Analysis…………………………… 9 Health History………………………….. 10 Family Genogram………………………. 11 Anatomy and Physiology………………. 12-13 Pathophysiology………………………… 14-17 Nursing Assessment Tool……………….

This is a longitudinal cross sectional study of all children and adolescents patients with LN following inPediatric Allergy and Immunology clinic, Children 's Hospital, Ain Shams University in the period between October 2013 and February 2014. Lupus nephritis in patients with pediatric onset SLE was diagnosed and graded on pathological basis according to 2003 ISN/RPS classification of LN into Class I: Minimal mesangial LN. Class II : Mesangial proliferative LN. Class III: Focal LN (≤50% of glomeruli)

narrowing the gap between the observed effects of placebo treatment and that of a potentially useful medication. The SLEDAI also doesn 't account for subjective symptoms like fatigue, dysphoria, arthralgia or myalgia, which might genuinely reflect lupus activity, and may be of high importance to patients (Fortin et al. 2000; E. Chang et al. 2002). An update version SLEDAI-2000 (SLEDAI-2k) was introduced and validated in 2002 based on findings in the preceding 10 days. SLEDAI-2k allow the documentation

Systemic Lupus Erythematosus What is Systemic Lupus Erythematosus? Systemic Lupus Erythematosus – otherwise known as lupus – is an inflammatory autoimmune condition and typically affects women of reproductive age and causes joint pain. Other manifestations of the disease include fatigue, rash, dry eyes/mouth, inflammation in other parts of the body, and blood cell abnormalities. One of the most worrisome complications of lupus is kidney disease, which is a common cause of dialysis dependence in

There are many varieties of lupus, but the most common one is Systemic Lupus Erythematous (SLE). SLE, commonly referred to as lupus, is a chronic autoimmune inflammatory disease that can affect all of the organs. There has not been a lot of research on this disease, but much of what is known about SLE is based on the signaling of the molecular abnormalities that is present in the disease (Signaling). It is believed that the cause of this disease is genetic, and triggered by unknown environmental

In Systemic Lupus Erythematosus, expression of the IL- 10 gene located on chromosome 1 (1q31-q32) is often inhibited. As the gene name implies, the gene encodes the cytokine IL-10, which is produced by inflammatory cells, such as monocytes and macrophages. (Yan, Bing, and Yi Liu. 2009). When this gene is inhibited the patient will show the signs of SLE, which are discoid lesions, and neurological disorder. When these symptoms begin to appear one can conclude that they have Systemic Lupus Erythematosus