Memantine

Major Alternative Products to Donepezil Apart from donepezil HCl (or brand name Aricept), there exist several other drugs prescribed to treat the symptoms of Alzheimer’s disease. Similar FDA approved drugs include galantamine, memantine, rivastigmine, and a donepezil and memantine mixture branded under the name Namzaric. Rivastigmine and

Razadyne or Galantamine is an alkaloid drug used mainly in the treatment of Alzheimer’s disease and dementia. It works through the mechanism of reverse competitive inhibition of the enzyme called acetylcholinesterase, which prevents the breakdown of the correspondent substrate acetylcholine, an essential chemical for the processes of thinking and reasoning. The Alzheimer’s drug market represents a 5.5-billion-dollar industry according to a pharma matters report published in 2009 by Thompson Reuters

symptoms. Memantine is one of the drugs used to treat AD patients. The U.S Food and Drug Administration (FDA) has approved two types of mechanisms for treating AD; Cholinesterase (an enzyme) inhibitors (e.g. donepezil, galantamine and rivastigmine): prevents break down of acetylcholine (a neurotransmitter/chemical messengers in body) and Blocking of NMDA (N-methyl-D-aspartate) receptors (e.g. memantine) (NMDA Receptors: Protein structures which are present on nerve cell surface). How Memantine works:

PBL 1 Assignment Jodi-Ann Crawford PNH 301 Instructor: Hyacinth Jackson October 13, 2015 Problem Based Learning #1: Alzheimer’s Disease Student Name: Date: SID: M.E. is a 62-year-old woman who has a 5-year history of progressive forgetfulness. She is no longer able to care for herself, has become increasingly depressed and paranoid, and recently started a fire in the kitchen. After extensive neurologic evaluation, M.E. is diagnosed as having Alzheimer 's disease

Although this study was well done, it leaves some unanswered questions. The biggest question is if memantine interferes with alpha tocopherol. While this study discovered that there is a connection between the two, it did not uncover what that connection was. More research should be conducted to determine the relationship between alpha tocopherol and memantine. Next, the vitamin E was taken orally via a liquid filled capsule. According to a study by Dr. Dan Engle published in 2009, compressed

Henry Lively, Joseph Miller, Thomas Zekoski September 21, 2015 Part 1 - Market Development Plan The trade name given to the focused product is Ebixa by Lundbeck, the drugs common name is ?memantine?, and the active substance is memantine hydrochloride. Figure 1: Molecular structure of memantine hydrochloride Ebixa is an Alzheimer?s medication, used to block NMDA (N-methyl-D-aspartate) receptors in the brain. This blocking process improves neural communication and reduces the symptoms of

In the beginning of this year, a research paper was published in The Journal of the American Medical Association. This paper discussed a clinical trial of which they used vitamin E and Memantine as a way to reduce the effects of AD. This trial started in 2007, but before that, there were trials studying the effects of antioxidants in AD patients. Both trials hypothesized that the use of antioxidants and another variable could reduce the effects of AD. One trial, studying the effects of antioxidants

CB will be reduce, rate of hospitalisation will be lessen and admission to NHP will be delayed. Pharmacological interventions of treating AD are by using anti-dementia drugs. Anti-dementia drugs are acetylcholinesterase inhibitors (AChEIs) and memantine. AChEIs which are donepezil, galantamine and rivastigmine have marketing authorisation in UK for treatment of mild to moderate AD. AChEIs work by preventing acetylcholinesterase enzyme from breaking down acetylcholine so that the concentration and

Some physicians also prescribe high doses of vitamin E for cognitive changes. The most common treatments today are cholinesterase inhibitors (FDA-approved drug), memantine (FDA-approved drug), vitamin E, and many alternative herbal treatments including caprylic acid, coconut oil, and coral calcium. With all of the treatments out there though, it is difficult to discern which is the best one. The purpose of this paper

environment. AD patients are known to experience symptoms such as memory loss in the early stages which develop into speaking difficulties to eventually hallucinations. The commonly used AD treatments include Donepezil, rivastigmine, galantamine and memantine. Only the last two will be discussed in this essay and novel treatments. The current treatments for AD focus on relieving symptoms