Naloxone

convenience to those who have to administer Naloxone because intranasal Naloxone has a preset dosage. While intranasal Naloxone is easier to administer, intravenous and intramuscular Naloxone administrators have a choice on the dose to give. Advanced EMTs have enough knowledge to choose the dose of Naloxone to give the patient to keep the patient alive. Intranasal was not approved until November of 2015 when the FDA approved a highly concentrated spray form of Naloxone (Strang et al. 576). Intranasal administration

I decided to write about a current issue involving the usage of Naloxone. There has been a debate going on for quite some time, about if all recue responders should carry Naloxone and administer it to people who have overdosed. Naloxone is described as a drug like morphine or fentanyl, that can cause an opposite effect of an opiate. It is either given by an injection or it can be done by a nasal spray. People debate that by administering this drug to someone who has overdosed is allowing them to

OTC Naloxone; Does it help, or hinder addicts? “Matty Rix grew up in a community that had much to offer a happy, adventurous boy. He took advantage of the open spaces and the forests and streams, whether riding his four-wheeler with friends or fishing and hunting with his father. But small-town, rural southern Maine also had something else to offer its curious youth: A steady supply of pain pills and other prescription drugs.” (Richardson, 2011) This is only one of the many sad stories of a promising

Administering Naloxone Hydrochloride (Narcan) Technically, Narcan is defined as a synthetic congener of oxymorphone, a potent antagonist of both endorphins and narcotics. In layman’s terms, Narcan is used to treat opiate overdose to reverse coma and respiratory depression; included in formulations of pentazocine to reduce the risk of abuse. In layman’s terms Narcan is a narcotic antagonist, that blocks the brain 's opioid receptors and reverses the process of an overdose. Naloxone Hydrochloride

Naloxone is an invaluable medication in healthcare professionals ' arsenal. According to Pasero (2012), standardized protocol for initiating resuscitation, naloxone administration, during an opioid-induced respiratory depression, is a must in every institution. As noted above Naloxone is a competitive antagonist of opioid receptors, primarily mu opioid receptor. Hence, the binding of the naloxone to the opioid receptors prevents attachment of opioids to the receptors. Therefore, the physiological

Naloxone Distribution: Ineffective way to deter opiate overdose Clarisse Goue UW-Madison School of Nursing 2017 Naloxone distribution: Ineffective way to deter opiates overdose In the United States, (US) the death from the use of opioid overdose has been increasing drastically. According to the National Institution on drug abuse, the number of deaths from opioids overdose has increased from 10-15k in 2002 to 30-35 in 2015 (NIH, 2015). This epidemic has become a global

controversy about whether or not the use of naloxone to reverse opiate overdoses is ethical. Overdose-related deaths are concentrated among those most affected by opiate dependence; the poor, racial and ethnic minorities, and individuals cycling in and out of the criminal justice system (Bazazi). Naloxone, more commonly known as Narcan™, is an opioid antagonist that counteracts the effects of opiate overdoses and in most cases saves the user. The use of naloxone on heroin overdoses is extremely beneficial

increasing number of programs have provided the opioid antagonist naloxone hydrochloride, the method of choice to reverse the potentially fatal respiratory depression caused by overdose of heroin and other opioids (CDC, 2010). Community coalitions, law enforcement, concerned friends, families and good Samaritans alike have each asserted that naloxone’s virtually untapped potential to save lives is enormous. Adding further standing, naloxone is on the World Health Organization’s (WHO) model list of essential

In the United States, more than 2 million people suffer from substance abuse disorders that correlate with use of prescription opioid painkillers. Over the past 15 years, overdose deaths due to prescription opioids have more than quadrupled. One of the underlying causes is the over prescription of pain relievers by physicians. This was demonstrated in 2013, with the writing of 207 million prescriptions for opioid pain relievers. Opiates can be classified as natural, synthetic, or semisynthetic

1. Signs of opiate toxidrome that this patient is exhibiting includes: hypothermia, bradycardia, hypotension, bradypnea, hypoxia, miosis, and unresponsiveness. 2. Narcan, also known as naloxone hydrochloride, is a pure competitive opioid antagonist used in the treatment of severe opioid toxicity. Naloxone’s mechanism of action is to bind to all opioid receptors including mu, kappa, and delta, and prevent the actions of opioid agonists resulting in reversal of life threatening respiratory depression