Neoplasm

Cancer lies resting in all of us; all the living organisms such as our bodies are consistently making defective cells1. This is how tumors are developed. Our bodies are provided with a number of mechanisms that can detect and keep such cells in check1. Breast Cancer (BC), is the most common malignancy found in women worldwide, and it is associated with high morbidity and mortality2. These breast tumors are made up of different characteristics of breast cancer cells3. However, toxicity and chemoresistance

Introduction Tumor-associated macrophages (TAMs) are a major cellular component of both mouse and human tumors (Pollard, 2004; Lewis and Pollard, 2006). High numbers of TAMs in human tumors usually correlate with reduced patient survival (Bingle et al., 2002; Zhang et al., 2012), and studies in mice have shown that TAMs promote important steps in tumor progression including tumor angiogenesis, cancer cell invasion, metastasis, and the suppression of adaptive anti-tumor immunity (Noy and Pollard,

Introduction Nanotechnology is a recently developed technique to produce nanoparticles. According to the definition from British Standards Institution, nanotechnology refers to the intentional design, characterization, production and applications of materials, structures, devices and systems by controlling their size and shape in the nanoscale range1. Nanotechnology covers versatile applications, such as medicine. Nanomedicine is defined as the field of medicine that aims to use the properties and

A Blessing My grandma was diagnosed with thyroid cancer in Honduras around two months ago. All of my family members (aunts, uncles, cousins, etcetera) lives in Honduras, where my parents are born and raised. Now my parents live here, in Tennessee. My parents call my family members back in Honduras to see how they are doing, and they call my parents to see how their doing. It happens quite often. This time my uncle (on my mom's side) called my mom, not to say " hey, how are you". But to discuss

Pancreatic Cancer Axia College (2009) Pancreatic cancer is an abnormal, uncontrolled growth of the cells in the pancreas, which is a digestive gland located behind the stomach. The pancreas is both an endocrine and exocrine gland. Cancer of the exocrine pancreas is more common than cancerof the endocrine pancreas. Pancreaticcancer is the fourth leading cause of cancer related deaths among men and women. Pancreatic cancer remains both a challenge to diagnose and even a greater challenge to treat

Circulating tumor cells (CTCs) Circulating tumor cells (CTCs), represent tumor cells that contain a heterogeneous populace of cells, including apoptotic tumor and viable tumor cells that have shed into the vasculature or lymphatics from a primary or metastatic tumor and are carried around the body in the circulation by undergoing phenotypic changes that are accompanied by a process called as epithelial-mesenchymal transition (EMT) 64-68. Evidence now suggests that the tumors has ability to make their

Targeted Alpha Therapy (TAT) is a promising method of the targeted radio-immunotherapy for the treatment of hematologic malignancies and extended to treat various solid cancers. Alpha-Immuno-Conjugate (AIC) is the diagnostic radiopharmaceutical compound used in clinical trials of TAT. Two essential elements of AIC must be included: a targeting antigen as a carrier that tends to attach the molecules on the surface of a specific tumor cell; and an Alpha emitter that undergoes Alpha decay to kill the

There are many type of cancer, once the abnormal cells grow out of control all cancers are starting. Cancers can cause serious illness and death if it is untreated. Trillions of living cells are made up in the body. Normal cells have the ability to grow, divide to produce new cells, and then die in a systematic way. During the early years of life, the normal cells confer the person to grow by dividing faster then the cells divide only to change worn-out or dying cells or to reform injuries when

Identified Population/Presenting Issue Cancer is a large number of diseases in which an abnormal cell divides into a mass of cells, which can metastasize to other locations in the body, where they then grow and disrupt normal bodily functions (Pardee, Stein, & Bronstein, 2008, p. 3-4). About 41 percent of people living in the United States can expect to be diagnosed with some type of cancer at one point or another in their life (The Psychosocial Needs of Cancer Patients, 2008). Due to the progress

Cancer starts with the normal cells in our bodies. Normal cells divide in processes called Mitosis and Meiosis which is how our bodies grow, heal and repair and when cells become old or are damaged, they die and new cells are created. However, when this cell division process goes wrong the cells become abnormal. Cell abnormalities occur when the cell makes errors whilst copying the genes. As the cell becomes more abnormal, the old and damaged cells do not die when they are supposed to but the new