Neurodegenerative disorders

CJD is a serious neurodegenerative disorder, a rare form of rapidly progressive dementia, with a 100% fatality within one to two years of onset. CJD belongs to a family of human and animal diseases known as the transmissible spongiform encephalopathies (TSEs). It is believed to be caused by an abnormal isoform of a cellular glycoprotein known as the prion protein that becomes toxic in an abnormal form (CDC) although Dr. Campellone suggest other proteins may play a role in this disease as well. Although

identified or there is any evidence of regression, children should be referred to a pediatric neurologist. A number neurodegenerative including metabolic and genetic disorders may present with similar signs and symptoms which are slowly more progressive are likely to be missed diagnosed as CP. Individually these disorders may be rare but collectively they are not. It is important that these disorders are correctly diagnosed as early as possible for a number of reasons. Firstly, some may be treatable, secondly

diagnosed? Huntington’s Disease (HD) is a genetically inherited, progressive, autosomal dominant, fatal neurodegenerative disease that’s characterized by behavioral difficulties, decline of cognitive abilities, abnormal involuntary movements (chorea), and muscle spasms (dystonia) (1). These characteristics help diagnose patients with HD, but a genetic test can be done to prove that one has the disorder. The gene responsible is that which produces the huntingtin protein in chromosome 4; the defect causes

Amyotrophic lateral Sclerosis (ALS) is a neurodegenerative disease. It is a disease which involves the degeneration of motor neurons. Not only does it degrade the motor neurons, It also degenerates the corticospinal neurons of the motor cortex. ALS is also known as Lou Gehrigs disease. This name came about after a New York Yankees baseball player developed this disorder and died from it in 1936. ALS is a heterogenous disorder. Multiple genetic factors contribute to the onset of ALS. More than 20

defined as an abnormality in an individual's genome and can vary in intensity from a discrete mutation of a single base in the DNA of a gene to a whole addition or subtraction in a set of chromosomes. Huntington’s Disease is an example of a genetic disorder in which nerve cells in the brain break down over time. It is a problem which occurs in every nation of the world. Passed from parent to child, a mutation in the normal gene is at blame for the serious conditions of this disease. More than 15,000

Progressive supranuclear palsy, otherwise known as PSP, is by definition a neurodegenerative brain disease that has no known cause, treatment, or cure. This disease affects the nerve cells making walking, balancing, vision, and other normal everyday actions extremely hard or impossible. There are many different symptoms that an individual may acquire when forming this brain disease. Such symptoms include: slurred speech, weakness in the eyes, weakened mouth movements, hard time swallowing, and loss

Autosomal Dominant is “one of several ways that a trait or disorder can be passed down (inherited) through families. The gene in question can be found on one of the non sex or numbered chromosomes also known as autosomal. The disease can be caused by a single copy of the disease associated mutation also known as dominant. Numerous people suffer from autosomal dominant disorders. Many factors contribute in developing an autosomal dominant disorder. An autosomal dominant disease is usually passed on from

Treatment of Sleeping 1 Disorders Should Be Considered in 2 Clinical Management of Parkinson’s Disease 3 4 5 Altair B. dos Santos1, George E. Barreto, PhD2, Kristi A. Kohlmeier, PhD3 * 6 7 1Department of Biological Sciences, Universidade Estadual do Sudoeste da Bahia, 8 Brazil. 9 2Departmento de Nutrición y Bioquímica, Facultad de Ciencias, Pontificia Universidad 10 Javeriana, Bogotá D.C., Colombia. 11 3Faculty of Health and Medical Sciences, Department of Drug Design and 12 Pharmacology, University

Huntington’s disease (HD) is a fatal genetic neurodegenerative genetic disorder affecting the brain. It results in uncontrolled jerking movements (chorea), cognitive and behavioural changes. HD leads to incapacitation of the patient and ends fatal. However, death rarely results from HD itself. It is typically due to complications of HD. HD was originally called Huntington’s chorea, because of the involuntary movements that looked like jerky dancing. Chorea is the Greek word for dancing. The majority

Understanding Schizophrenia 4 Understanding Schizophrenia Schizophrenia is a disorder of varying symptoms, in fact until the current edition of the DSM-V this disorder was broken into subtypes such as catatonic, disorganized, paranoid, undifferentiated, and residual. There many facets of schizophrenia such as auditory hallucinations, delusions, social isolation, as well as intense suspicion or agitation, each of which contributed to the previous subtypes of schizophrenia. Today, individuals with