Oligodendrocyte

Neurons and Skeletal Muscle The human body uses unspecialised sperm cells which come from egg cell from the female or sperm cell form the male (zygote) then they specialise into neuron and skeletal muscle or any other type of cell. The stem cells are the building blocks they go through a various process called stem cells differentiation which allows them to be specialise. • The zygote turns into a morula which is called a totipotent; totipotent is a whole organism which can turn into multiple types

Please consider my application for the position of DBT-Cambridge Lectureship. I am currently working as a senior postdoctoral fellow at the Cambridge Stem Cell Institute. My interdisciplinary research focuses on identifying novel approaches to stimulate central nervous system (CNS) myelin regeneration (remyelination) by endogenous adult neural stem cells. Myelin is a fatty membrane structure around nerve cells and serves to increase the speed of electrical communication between neurons. Myelin is

occlusion and reperfusion, in an animal model of vascular depression, resulted in reduced myelin breakdown and oligodendrocyte loss compared to placebo-treated mice on post-operative day (POD) 7. For late stage of recovery (POD40), quetiapine treatment resulted in enhanced oligodendrocyte maturation relative to placebo. The results suggest that quetiapine is a potential intervention for oligodendrocyte damage and this may

star. The role of an astrocyte is to support the neurons. They maintain chemical concentrations, remove waste, repairs, as well as playing a role in the blood brain barrier. Oligodendrocytes are found in the CNS and provide the myelin sheath. Schwann cells are found in the PNS and provide the myelin sheath. Both Oligodendrocytes and Schwann cells hold the same responsibilities. The Microglial cell ingests cells and pathogens and play a role in immunity. Question 5: Cerebrospinal fluid is the liquid

through asymmetrical division and self-renewal. The pluripotent stem cells that will be the focus of this review are the neural stem cells or NSCs. NSCs are the cells responsible for producing all of the neural cells: neurons, astrocytes, and oligodendrocytes. These cells are present in during both embryogenesis and in certain populations in the adult brain. There differentiation and patterning is regulated by several factors. Regulation of Differentiation, Patterning, and Migration Intrinsic

The response to a SCI can be separated into three discrete, partially overlapping phases: acute (seconds to minutes after SCI), sub-acute (minutes to weeks after SCI), and chronic (months to years after SCI). The acute phase centers around the primary SCI damage resulting from the trauma, resulting in immediate physical and biochemical cellular changes. These include direct cell death, vasospasms (leads to vasoconstriction, ischemia, and tissue death), plasma membrane compromise, disruption of ionic

now become specialized and develop into astrocytes and oligodendrocytes. These cells are extremely important in the next stage of myelination. Myelination is the stage of neuronal development that is initiated postnatally. After the baby is born the newly specialized glia cells begin constructing the fatty sheath around the axon, need for the speed and effectiveness of the neural transmission between all the neurons in the brain. Oligodendrocytes are responsible for the myelin produced in the central

Sensory Input, Integration, and Motor Output Sensory receptors detect when a hot spoon touches your skin which is caused by the sensory input. Once the receptors feel the input the nervous system decides what to do about it; this is integration. Motor output is what is done about the input, whether you scream or jerk away from the hot spoon. So the response that you get from the integration is the motor output when is acts upon the body. Central Nervous System The central nervous system is made

The Pathology of Multiple Sclerosis Introduction Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević,

autoimmune process that develops when a previous viral insult to the nervous system has occurred in a genetically susceptible individual. B lymphocytes, plasma cells, and activated T cells, along with proinflammatory cytokines, cause inflammation, oligodendrocyte injury and demyelination. Early inflammation and demyelination lead to irreversible axonal