Objective The current experiment introduces the concept of green chemistry on microwave heating to synthesise aspirin, instead of using conventional heating methods. Introduction Aspirin synthesis is a popular experiment undertaken in most organic chemistry teaching laboratories (Montes et al., 2006). Most experimental procedures for aspirin synthesis are undertaken to study the carbonyl nucleophilic substitution reactions either under basic or acidic conditions (Polshettiwar and Varma, 2008; Varma
attack carbonyl groups that can form substituted alcohols after the protonation step. The reaction occurred as follows. The first step consisted in the formation of the Grignard reagent. That was done through the use of an organic halide provided in the lab and Magnesium. The organic halide used was bromobenzene. The second step consisted of reacting the Grignard reagent formed in the first step with benzaldehyde. The third and final step consisted of using the product of the second step and diluting
Grignard Reactions Introduction Grignard reactions are of extreme importance in synthesis of many organic compounds. Because of the extreme nucleophilic tendencies of the Grignard reagent (typically denoted RMgX, where R is an organic nucleophile, and X is a halide), we find that Grignard reagents are extremely useful for the addition of organic fragments. The Grignard reagent’s extreme nucleophilicity can be explained by its unique bonding abilities. Because the carbon-magnesium bond is neither
In the Grignard Synthesis of Malachite Green, 4-bromo-N,N-dimethylaniline (aniline) and Magnesium (Mg) in the solvent THF were reacted to form the Grignard reagent. From there, ester methylbenzoate was used, along with HCL to yield Malachite Green. It is important to note that the Grignard reagent is very moisture sensitive. Due to this, it is possible for side reactions to occur. Due to the basicity of the Grignard reagent, any exposure to moisture or water will cause the reagent to deprotonate
than carbons. So the result is a partially negative charged, nucleophilic carbon. That nucleophilic carbon can then be taken and used to attack an electrophilic carbon, thus creating a new carbon-carbon bond. This is the basis for organometallic chemistry. Grignard reactions specifically use magnesium to form the carbon-metal complex. The carbon-magnesium complex is called the “grignard reagent”. This is a non-chain radical mechanism. In this experiment, grignard reagents are prepared. This starts
Statement of Purpose Introduction / background Chemistry is ubiquitous and its prevalence is evident in everything right from environment, biology and even in technology. It is this versatility, which aids me in gaining insight in every field of science. Being a graduate in Bio-analytical Chemistry and Organic chemistry, my enthusiasm and inclination grew towards quantitative and qualitative analysis of natural and synthetic compounds in research laboratory. It is with this passion, I look forward
Discussion The Grignard reaction involves the use of a Grignard agent, or an organomagnesium halide, to an aldehyde or a ketone to form either a secondary or tertiary alcohol, respectively. Using this reaction with formaldehyde leads to a primary alcohol. Grignard reagents can also be used in important reactions such as in the addition of an excess of a Grignard reagent to an ester to give a tertiary alcohol so that the two alkyl groups are symmetrical. Grignard reagents are formed though the interaction
Ecstacy.MDA. Nutmeg. A ubiquitous spice that can be found in kitchens worldwide, nutmeg has been harnessed in cooking, rituals, and a multitude of different ways across multiple cultures for millennia (Baxamusa, 2011). Its most common use in near day-to-day cooking is something that is not given a lot of thought to, but with Drug culture becoming increasingly prevalent in younger demographics, nutmeg has become a cheap and easily sourced alternative (Shafer, 2010). Through analysis of its chemical
ABSTRACT: In this account, phosphorylated chitosan (PCS) were first deposited on the surface of multi-walled carbon nanotubes (MWNTs) via chemical modification to obtain functionalized MWNTs-based PCS (PCS-MWNTs). Then, a series of PET fibers with MWNTs or PCS-MWNTs were prepared via melt spinning. The microstructure and molecular structure of MWNTs and PCS-MWNTs were characterized by field-emission scanning electron microscopy (FESEM) and Fourier-transform infrared (FTIR spectroscopy. The morphological
My Program of Study By; Lilly Reagan Chemistry of cosmetology is my choice for my program of study, because science and cosmetology really do “go hand in hand”, as most people don’t realize it that much, nor pay attention to it. Chemistry Cosmetology is where beauty products are made from combinations of chemicals and fall into the realm of the program. Chemicals, meaning products like dye. People who work with hair have to know what’s in the chemicals they put into people’s hair, they also need