Paper chromatography

Title: Competing Nucleophiles (Exp 24, pp 211-221, pp 808-823, pp 836-842) Purpose: The purpose of this experiment is to determine the nucleophilic strength of chloride and bromide ions as it reacts with 1-butanol (n-butyl) and 2-methyl-2-propanol (t-butyl alcohol) under SN1 and SN2 conditions. Method: 40 g of ice and approximately 30 ml of sulfuric acid is cautiously added to a 100 mL beaker respectively. Weigh 7.6 g of ammonium chloride and 14.0 g of ammonium bromide and place it in

A general trend in dual ACC1/ACC2 inhibition was often encountered among the 125 compounds tested: good ACC1 inhibition was linked to good ACC2 inhibition.4 The same group elaborated on this study by examining the structure–activity relationship (SAR) for the pyrazole part and the substitution at position 9 of the 1,9-diazaspiro[5.5]- undecane. In this study, additional pharmacokinetics were studied along with the IC50 values for ACC1 and ACC2, such as the lipophilic ligand efficiency (LipE)

Running head: DR PEPPER/7UP, INC. Dr Pepper/7Up, Inc. – Case Analysis MKTG610 Case Recap Squirt soft drink is a caffeine-free, low sodium carbonated drink designed and created by Dr Pepper/7Up, Inc... This powerhouse drink is a wonderful creation of distinctive grapefruit juices, which gives it its fresh citrus taste. Due to its unique flavoring as a soft drink, Squirt is one of the best-selling carbonated drinks in the United States (Kerin & Peterson 2009) The key elements

Table 6.1: System suitability results of Lamivudine, Abacavir and Dolutegravir Parameters Lamivudine Abacavir Dolutegravir Retention time 1.763 2.247 3.175 USP plate count 2755 2190 2693 USP tailing 1.23 1.25 1.29 Standard area 935905 195063 27100 6.3.2 Assay of pharmaceutical formulation The proposed method was effectively applied to find Lamivudine, Abacavir and Dolutegravir in their tablet dosage form. The results obtained for Lamivudine, Abacavir and Dolutegravir were comparable with the corresponding

presence of boron trichloride an ester derivative. Acid BCl3 RCOOH + ClCH2CH2OH → RCOOCH2CH2Cl + H2O b. Tetra-butyl-ammonium hydroxide (TBH): forms butyl ester with derivative or carboxylic acid that improves the retention time in the gas chromatography column. TBH

chemistry brought me an award in "Srujan" project (Neutron Activation Analysis) associated with Nehru Science Center. The project edified my mind with practical knowledge and expertise in TLC, Crystallization, NMR, Spectroscopy (UV, Visible and IR), Chromatography (HPLC and Gas) and stereochemistry.

Table.2 shown the best results of vertical resolution used in shorter pulse duration is better for the higher frequency and very similar for the 1 GHz, 800 MHz and 500 MHz. More which explains why the results obtained in Tables 3 was the same for both frequency. Because of the different materials used in the experiments metallic and wooden bars, the resolution show the metal bars are worsen, due to their higher electromagnetic contrast, amongst other things. The second reflector, so a bigger separation

Microsponges – a novel carrier for resiquimod Microsponge is a polymeric drug delivery system composed of spherical particles ranged in micron size and loaded with active pharmaceutical ingredient. Microsponges have maximum residency on the skin and slow release rate. Resiquimod is a candidate drug to be entrapped in microsponge drug delivery system. Formulation of resiquimod loaded microsponges was done using oil in water emulsion solvent evaporation method. The method had two phases, organic

Gel-Filtration Chromatography is a commonly used method used in order purify a protein from a mixture, by means of separations. Different biomolecules differ in size, or their molecular weight. In the gel matrix inside the chromatography column, there are gel beads which are porous to allow certain sized molecules to enter. The molecules that are able to enter the pores of the gel, are held in stationary phase and will elute from the column later on, these are usually smaller, to medium sized molecules

In Table 1, fluorene travels further up the TLC plate versus fluorenone since a more nonpolar 80:20 pentane-ether developing solvent is used. Since fluorine is more nonpolar than 9-fluorenone, it will be more soluble in the highly nonpolar solvent and enter the mobile phase easier than the polar 9-fluorenone. Fraction 2 is expected to have two different spots because this is the collection of the eluted solution between Fraction 1 and Fraction 3, where the fraction contains both the remaining fluorene