Phage therapy

a) Phage therapy involves the use of bacteriophages to treat specific pathogenic bacteria. The bacteriophages infect or kill pathogenic bacteria upon encounter with them. In 1915, Frederick Twort discovered the viruses of bacteria (Abedon, 2011). The bacteriophage era began when Felix d'Hérelle published a seminal publication that demonstrated “un bactériophage obligatoire” (Abedon, 2011) Soon after, microbiologists began to include the phages idea into their ideas. Novel therapies are needed to

Investing in alternate approaches to medical treatment is necessary and because of that bacteriophage therapy is starting to gain interest. The problem that arises is that

Before the age 20, I had already been to three different countries and many cities. Which allows me to meet with different people, experience different cultures and encounter different believes. I was born in Mundemba, a small town in the South West region of Cameroon. Cameroon is a located in the western part of central Africa. Life in Cameroon was simple and fun. I spent the first nineteen years of my life there during which I completed high school. After developing and immense love for the sciences

virus will cause damage to their intestines because that is solely what cholera targets, and the purpose of the phages are to combat the cholera bacteria, which would in turn help their intestines. 5. The release of a toxin from the cholera bacteria is what causes people to experience the dreadful symptoms. A negative health concern of killing the cholera at a quick rate is that since the phages will prevent symptoms from increasingly becoming worse, the “dead” cholera in the intestine may sit there for

Bacteriophages (or in short, Phages) are viruses that solely infect bacteria, in fact, each Phage can only infect a very specific type of bacteria in order to survive and replicate. like other viruses, Phages need a bacterial host in order to replicate their viral DNA , RNA etc… Phages are also named after the strain of bacteria which they infect eg: coli phages infect the bacteria E-coli. each Phage can vary in shape and size but they all contain Capsids (protein coats) which surround their viral

There are several advantages to phage therapy with target specificity being one of the main ones. Most phages will only lyse bacteria of a particular species or a specific strain meaning that the human microbiota should not be affected. In contrast, antibiotics are less specific and so treatment usually disrupts this flora, allowing opportunistic bacteria to thrive. This specificity is also a limitation as the bacteria causing the infection needs to be determined otherwise the treatment is likely

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A Planet of Viruses For centuries new viruses have been discovered each and everyday by thousands of different scientists. These viruses affect the lives of almost a billion people. Even though many of these viruses can be harmful to the human body, they have played a phenomenal role in the biological advances over the past century. They move DNA between species, regulate vast populations of organisms, and provide new genetic material for evolution. Viruses influence every single species on earth

1.5.1.3 R-type pyocin: Therapeutic potential The potential of R-type pyocin to be developed as a therapeutic was realized immediately after its discovery. As early as in 1967, Higerd et al showed that R-type pyocin was safe to administer in animals [77]; it did not have a lethal effect on mice and rabbits when injected in high concentration intraperitoneally. Since then, six studies have specifically looked at the therapeutic potential of R-type pyocins in animal models. Bird and Grieble, in 1969

Phage therapy has many applications in medicine, dentistry, veterinary science, and agriculture. In some cases the phage therapy can be very effective offering some advantages over antibiotics. Bacteria also develop resistance to phages, but it is easier to develop new phage than new antibiotic. When bacteria develop resistance, the opposite phages are evolved naturally. Phages have special advantage as they penetrate deeper as long as the