Route of administration

bad, and less medicine gets to the target tissue. 2.) Sublingual- placing the tablet under the tounge or between the cheeks(buccal route) should be small and lipid sloubile Advantages are fast absorbing, less first pass effect, and drug no longer has any effect when spit out. Disadvantages are inconvenient, unpleasant taste, or patient might swallow it. Rectal Route- drug is given directly into the anus comes in solid form(suppositories) or liquid form(enema) used a lot in older patients can have

Unit 616 1.1.2.1.2.2.2.3.2.4.5.1.5.3.5.4.5.6.5.7 There are several current legislation, guidelines, policies and protocols relevant to the administration of medication. These are The medicines Act (1968), Misuse of Drugs Act (1971), Misuse of Drugs Regulations (2007), Health Act (2000) The Care Standards Act (2000), Domiciliary Care Agencies Regulations (2002) Control of Substances Hazards to Health (2002), Hazard Waste Regulations, Controlled Waste Regulations (1992), The Handling of Medic9ines

Suppositories are the frequently used dosage forms prescribed through rectal route. However, suppositories have the limitation of prolonged onset of action which can be attributed to poor drug release properties of suppository base. Surfactants can increase the drug release to aid absorption by reducing the interfacial tension between rectal fluids and the suppository base. The objective of this study was to examine the effect of different concentrations of sodium lauryl sulphate and tween 80 on

To help with the quick admission, intranasal administration is a convenience to those who have to administer Naloxone because intranasal Naloxone has a preset dosage. While intranasal Naloxone is easier to administer, intravenous and intramuscular Naloxone administrators have a choice on the dose to give. Advanced EMTs have enough knowledge to choose the dose of Naloxone to give the patient to keep the patient alive. Intranasal was not approved until November of 2015 when the FDA approved a highly

ASM34 1.1 Legislation – The Medicines Act, Control of Substances Hazardous to Health (COSHH) Regulations, The Health and Safety at Work Act, The Misuse of Drugs Act, The Misuse of Drugs (Safe Custody) Regulations, Health and Social Care Act The Medication Policy and procedure and Mars Handbook covers assessment of individuals’ needs, administering, storage, recording and disposal of medicines including their effects and potential side effects ASM34 2.1 Common Types of Medication, Effects, Potential

the nasal route has established itself as a competitor and an alternative route over other routes of administration. It provides a higher degree of patient compliance and drugs can be painlessly self-administered by the patient (Illum, 2003). Drugs administered through nasal route are absorbed rapidly and can reach therapeutically effective plasma levels quickly due to highly permeable membranes and rich vasculature of the nasal cavity (Majithiya et al., 2006). In addition, the nasal route offers further

effect due to partial degradation of the drug before it reaches its destination is a major concern. For example, a drug administered orally may undergo changes in the stomach due to the action of gastric enzymes. Drugs administered through enteral routes undergo a first pass effect, which is the term used for the hepatic metabolism of a pharmacological agent when it is absorbed from the gut and delivered to the liver via the portal circulation. These processes lead to premature drug loss due to drug

DESIGN FORMULATION AND EVALUATION OF GASTRORETENTIVE FLOATING TABLETS OF STAVUDINE Mourya Adarsh*, Mrs.P. Haritha Sunil*, Praveen Kanna, Sampath.M Department of Pharmaceutics, St.Pauls College of Pharmacy, Hayathnagar, Telangana, India Abstract: The purpose of the present research work was to design, formulate and evaluate the floating tablets of Stavudine, a gastro retentive drug delivery system. Direct compression was used to prepare the tablets using HPMC K4M, HPMC K15M and Carbopol 974(p) as

Background Organ transplantation is a surgical procedure of replacing a failing or diseased organ with a healthier donor organ. In 2011, nearly 80% of 4500 Canadians needing an organ transplant are waiting for a donor. Of which, 35% died while waiting for an organ. In 2014, 2356 organs were transplanted and over 4500 patients were still waiting for the donor. The statistics prove that organ transplantation is critical and the transplanted organ must stay healthy for the rest of the recipient’s life

be either not possible or difficult. Autoinjectors are very much useful in emergency situations as it can make self administration possible. It can be used to deliver drug either by intramuscular or subcutaneous injection. Autoinjector has got many advantages. It delivers the drug fast and gives better bioavailability as it deliver the drug with a spray effect during administration. It is convenient and since the needle is inside the vial itself, the needle phobia can be avoided. 1.1 Natural disasters