Route

Results and discussion 6. References 1. INTRODUCTION The main goal of pharmaceutical formulation is to achieve better therapeutic activity in the shortest possible time by using smallest quantity of drug administered by the most suitable route. Oral drug delivery is the simplest and easiest way of administering drugs, Because of the greater stability, smaller bulk, accurate dosage and easy production, solid oral dosages forms have many advantages over other types of oral dosage forms. Therefore

Ophthalmic drug delivery is the most complicated drug delivery due to its unique anatomical and physiological barriers. Viruses, bacteria and fungi are the three most common pathogens causing various ocular disorders. The infections can be either local, where only the ocular tissues are infected or systemic where the infection spreads to various other organs. Immunocompromised patients are more prone to these infections. While some infections are self-limiting and benign, others are associated with

DESIGN FORMULATION AND EVALUATION OF GASTRORETENTIVE FLOATING TABLETS OF STAVUDINE Mourya Adarsh*, Mrs.P. Haritha Sunil*, Praveen Kanna, Sampath.M Department of Pharmaceutics, St.Pauls College of Pharmacy, Hayathnagar, Telangana, India Abstract: The purpose of the present research work was to design, formulate and evaluate the floating tablets of Stavudine, a gastro retentive drug delivery system. Direct compression was used to prepare the tablets using HPMC K4M, HPMC K15M and Carbopol 974(p) as

L ike a salami cutter, the rivals of the RGA continued cutting away at its holdings outside of the Children’s Paradise, thin slice by thin slice. The regular crews and groups it had, in addition to the recently formed Volksbesatzung and friendly BUG crews, could not stem the rising tide. For the average RGA crew found itself going up against anywhere between five or six different factions at once. This resulted in the RGA to being completed outnumbered. Yet despite being outnumbered, coupled with

negative bacilli. Structurally they have two aminosugars linked to hexose nucleus through glycosidic linkage. Aminoglycosides are obtained from Streptomyces or Micromonospora species. Aminoglycosides are highly polar and hence are not absorbed by oral route. All aminoglycosides resemble in their pharmacokinetic properties. They will not penetrate into the central nervous system and normally administered topically, intravenously, intramuscularly or intrathecally. Most of the parenteral aminoglycosides

establishing the Cape of Good Hope as a Dutch colony in Africa. The Portuguese were able to import Porcelain from the Ming Dynasty, and spices from the Malaysia though the new trade route. They would later expand their influence over the nations by building forts to protect their trading routes. However, due to their long trading route around the Africa and growing competition from other European nations, meant that their influence would not last. Through series of wars with the Dutch and the English, the

will be loaded in trains and trucks from the Iraqi Grand port of Al-Faw Southern of the country, and then will travel across the country to Turkey and then to Europe. This would give shippers companies an alternative to traditional but no longer route around the Arabian Peninsula, up through the Suez Canal of Egypt. Iraq is a very rich country and has a lot of potential and

6. PREPARATION OF SEDDS Method of preparation may vary according to the dosage form of the formulation. The techniques can be implemented accordingly to the stability, sensitivity and adaptability of the drug excipients to self-emulsified form. In olden days, SEDDS are prepared in the form of liquid state where it will be enclosed by hard or soft gelatin capsules. By this, it helps to enhance oral administration and later on it is known to burden in the formulation. Main disadvantages are low drug

and 16th centuries, the Italians and Muslims had control of the Mediterranean. Because of this, countries such as Portugal lacked access to Asian trade routes, since they lacked the resources to break through “the Italian dominated trade of the Mediterranean” (Arnold 4) Such countries were forced to explore and expand in order to find new routes around the world to reach Asia, causing them to search for goods and trade beyond their borders, acquiring land and resources along the way, which in turn

Transmucosal route of drug delivery is widely accepted as a suitable way for administration of drugs via buccal mucosa for local and systemic applications. Compared to other transmucosal routes, buccal mucosa is approximately an immobile, highly accessible mucosa that characterized by wide area of smooth muscles1. Moreover, buccal drug delivery systems offer various advantages including the direct entry to the systemic circulation through the internal jugular vein avoiding first pass metabolism and