Solubility

Megan  Ly   Chemistry  231L   February  20,  2013     SOLUBILITY     Purpose:  To  better  comprehend  solubility  behavior  by  investigating  the  solubility  of  various   substances  in  different  solvents,  looking  at  miscible  and  immiscible  pairs  of  liquids,  and   observing  the  solubility  of  organic  acids  and  bases.     Reference:  Pavia

Jacinta Houng Comparing the Solubility of Chemicals in Water “Water is known as the “universal solvent” because so many different substances dissolve in it and we rely on this for many of our daily needs.” Introduction: Water is known as the ‘universal solvent’ as it is capable of dissolving a variety of different substances and dissolves more substances than any other liquid. However the ability to be soluble depends on a substances polarity and bonding. This then contributes to the various ways

-chemist understands solubility as a measure -a chemist would say that solubility is the max solute that can be dissolved in the solvent until it reaches equilibrium -when the solution reaches equilibrium, there can be no more solute added to the solvent: it won 't dissolve anymore, it will just rest at the bottom as residue -the chemical formula of salt is NaCI -1 ATM is standard air pressure for earth -the unit for solubility of water it for ex: 357.00 g/L -when the solubility is put in the solvent

NaCl or sodium chloride salt has one of the highest levels of solubility in water due to its ionic bonds, which easily breaks apart in a polar solvent meanwhile, sodium chloride is not soluble in hexane because of the structure and polarity of hexane that is non-polar. Thus, when NaCl is put into hexane, the charged particles and the non-polar particles would stay altogether resulting in no mixing or dissolution. Naphthalene is non-polar covalent solute therefore it dissolves in non-polar solvent

could affect different patients when developing these drugs. Solubility is one of these properties, and it is the ability of a solid, liquid, or gaseous substance to dissolve in a solid, liquid or gaseous solvent, and it is critical to absorption into the body. In drug discovery over the years, the number of insoluble drug candidates has increased recently, with almost 70% of new drug candidates showing poor water solubility. The solubility of a substance fundamentally depends on the solvent used, as

RESULTS Determination of solubility of fenoprofen The solubility data is shown in Table I and it is presented in Figs.1, 2 and 3. The solubility of fenoprofen amongst various oils investigated was found to be highest in oleic acid (198.93±2.91mg/ml) followed by triacetin, labrafil M1944, capryol 90. The solubility of drug was insignificantly different between labrafac lipophil, IPM, and labrafac PG. Amongst surfactants, labrasol showed maximum solubility (129.17±1.4mg/ml) followed by tween 80,

Mateo Castro April 3, 2013 Lab Partner: Unur Abdul Kader T.A: Katie Experiment 22: Molar Solubility, Common-Ion Effect Abstract The purpose of this experiment was to determine the molar solubility, the solubility constant, and the effect of a common ion on the molar solubility of calcium hydroxide. To accomplish this the experiment was split into two parts; part A and Part B. in Part A of the experiment a standardized 0.05 M solution of HCl was titrated into a 25 mL solution of saturated

1. The goal of the solubility experiment is to determine weather a substance is soluble or insoluble using various techniques. In part A of the experiment the solubility of different substances in different solvents will be investigated. To achieve the goal of part a 40 mg of benzophenone will be placed into test tubes. Each test tube will contain a different solvent and one will serve as a control. A spatula will be used to stir the contents in the test tube, once this step is complete it will be

may increase or decrease the solubility of a solute in a given solvent. The effect of an additive depends very much on the influence: it has on the structure of water or its ability to compete with solvent of water molecules. A convenient quantitation result of the solute additive on the solubility of another solute may be obtained by Setschenowequation. Log S0/S = KCa where S = solubility in the presence of additive Ca = additive concentration S0 = solubility in the absence of additive

Discussion of Instructional Strategies The lesson titled “The Solubility of a Salt Lab” was a lab practical that incorporated adjustments for both the ELL student and the student with an IEP. The ELL student was partnered with a highly motivated and helpful student who often displayed patience when working with peers. This student was allowed to give oral responses to written responses on assessment, but then was also be encouraged to attempt to write responses as well. The student with an