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  • The Effects Of Statins On The Treatment Of Many Diseases

    1147 Words  | 5 Pages

    Statins are drugs used in the treatment of many diseases including hypercholesterolemia, ischemic heart disease (angina, chronic heart disease and myocardial infarction), cerebrovascular accidents and peripheral arterial disease. Adults with a history of cardiovascular disease (CVD) or those with a 10-year risk of developing CVD should start statin therapy as a prophylactic measure. As a result of all these indications, statins are one of the world’s most prescribed drugs (1). Many forms of statins

  • Effects Of Statins On Risk Of Stroke And Preventing Cerebral Ischemia

    870 Words  | 4 Pages

    ASSESMENT OF THE EFFECT OF STATINS IN LOWRING THE RISK OF STROKE AND PREVENTING CEREBRAL ISCHEMIA IN PATIENTS WITH HYPERCHOLESTEROLEMIA Introduction Stroke is a world wide common disease with its occurrence depending on multiple risk factors involved, one of which is high blood cholesterol and LDL level, it is thought that lower cholesterol level decreases the incidence of cerebrovascular ischemia (doc3.pdf) which has been concluded from many clinical trials conducted for the purpose of understanding

  • Ezetimibe On Statin Therapy After Acute Coronary Syndromes

    1319 Words  | 6 Pages

    Camille Pargo Journal Club 7/15/2015 Article Title: Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes Authors: Cannon CP, Blazing MA, Giugliano RP, et. Al Executive Committee: Representatives from Thrombolysis in Myocardial Infarction (TIMI), Duke Clinical Research Institute (DCRI), and Merck & Co., Inc. Enrollment Centers: Representatives from 1158 enrolling centers in 39 countries Journal: The New England Journal of Medicine Funding: Merck Journal citation: N Engl J Med 2015;372:2387-2397

  • The Effects Of Statins And Its Effect On The Liver Disease And Stroke ( Doc1 )

    895 Words  | 4 Pages

    effects of statins, drugs that have been manufactured primarily for the purpose of controlling blood cholesterol level, statins are defined as a family of drugs that control and inhibit cholesterol production by acting through binding to 3-hydroxymethyl-3-glutaryl coenzyme A (HMG-CoA) reductase, by this mechanism the end result will be a lower LDL level in the blood which in turn benefits the outcome of many states of disease including cardiovascular disease and stroke (doc1.pdf-[1]) Statins has multiple

  • Statin Pills, Including Lipitor, Which Can Be Prescribed

    1364 Words  | 6 Pages

    Statin pills, including Lipitor, which can be prescribed to decrease cholesterol levels, paintings partly through interfering with the activity of HMG-CoA reductase. If your cells take place to want more LDL cholesterol below certain circumstances, but the statin drug is blockading this essential enzyme, your cells won 't be able to make cholesterol whilst wished. And what’s worse is that the cholesterol synthesis pathway doesn’t just make LDL cholesterol; branches of this same pathway are liable

  • The Protective Effects Of Statins On Clinical Outcomes Among Bacteremic Patients

    1144 Words  | 5 Pages

    Methodology- Specific Aim 2 In the second part of this proposed dissertation, the protective effects of statins will be evaluated by quantifying the effects of their use on clinical outcomes among bacteremic patients in a large, nationally representative cohort. A retrospective cohort study design will be used to assess multiple outcomes, such as inpatient mortality and length of hospital stay, among statin exposed v/s non-exposed patients. A retrospective cohort study is an analytical study in which individuals

  • What is Hyperlipidemia?

    1159 Words  | 5 Pages

    Introduction Hyperlipidemia is the abnormal elevation of any lipoproteins present in the blood. HMG-CoA reductase inhibitors (statins) are commonly used for the treatment of hyperlipidemia, specifically lowering the levels of low-density lipoproteins (LDL) levels. As with most classes of medications, there are many potential side effects. A less common but serious side effect of statins is myopathy. Myopathy is a dose-related side effect that causes skeletal muscle weakness, aching, cramping, pain, stiffness

  • Potential Cardioprotective Effects Other than LDL Lowering

    1071 Words  | 4 Pages

    Lowering Cardioprotective effect of statins is ascribed by lowering LDL-C and improving the lipid profile as reflected in plasma cholesterol levels. Statins and Endothelial Function Vascular endothelium plays a role in both vasoconstriction and relaxation, while hypercholesterolemia by modulating arterial tone adversely affects this process. However, endothelial function is improved by statin therapy due to production of the vasodilator nitric oxide. Statins and Plaque Stability The degree of rupture

  • Essay On Statins

    993 Words  | 4 Pages

    On the surface, statins, a class of drugs, appear to be a no-brainer. They inhibit the enzyme that the body uses to create cholesterol, essentially slowing down the production of cholesterol in order to prevent a build up in the arteries and causing a stroke. Consequently, they are prescribed to those who have high cholesterol levels and are at risk of cardiovascular diseases. However, a variety of studies show that this medicine is not as simple as it appears. With the CDC reporting about 25% of

  • Coenzyme Q10 Essay

    781 Words  | 4 Pages

    production and it is also one of the most powerful antioxidants available. Unfortunately as we age our bodies have rapidly declining CoQ10 levels. Many things are responsible for depleting CoQ10 levels which include toxins, stress, aging, as well as the statin drugs (HMG-CoA reductase inhibitors) that Americans take for heart problems and high cholesterol.