Substitution

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  • Nucleophilic Substitution

    1760 Words  | 8 Pages

    Nucleophilic Substitution Samantha Gutierrez Nucleophilic Substitution Introduction: The purpose of this lab is to investigate how different factors affect the rate of SN1 and SN2 reactions. SN2 reactions proceed via a one step mechanism in which the incoming nucleophile attacks the electrophilic carbon center from the opposite side of the leaving group. This reaction mechanism implies that the stereochemistry of a chiral center will be inverted. SN1 reactions proceed via two steps, slow

  • Importance Of Substitution And Elimination Reactions

    1461 Words  | 6 Pages

    Substitution and Elimination Reactions Substitution reactions replace a functional group with a new group. These reactions compete with elimination reactions in which a group is eliminated and a π (pi) bond is formed. Substitution reactions occur when a nucleophile is added to an electrophile/substrate. Elimination reactions occur when a base is added to an electrophile/substrate. The electrophile must contain a leaving group to be considered a substrate. Alkyl Halides Alkyl Halides are the common

  • The Substitution Mechanisms ( Sn1 And Sn2 ) With Reactions

    2391 Words  | 10 Pages

    This paper was written in order to relate nucleophilic substitution mechanisms (SN1 and SN2) with reactions that involved converting alcohol-containing compounds to alkyl halides. This experiment was conducted by combining the initial alcohol with reagents and heating under reflux when necessary. It was determined that mechanistic pathways of substitution depend principally on the structure of the initial alcohol; that is, substrate is considered primary, secondary, or tertiary. Synthesis of 1 (46%)

  • Nucleophilic Substitution SN1-SN2

    749 Words  | 3 Pages

    The nucleophilic substitution SN1/SN2 typically occur in a competitive regime. There are various conditions that define the predominant reaction mechanism taking place. Since SN1 leads to the racemic mixture, SN2 is more popular in asymmetric organic synthesis. So, detailed computational studies of model SN2 reactions have been carried out during the last three decades[2-6, 9]. The influence of solvation of the nucleophile with several common solvents on the rate constant of the reactions F-(Sn)

  • Substitution Reactions ( Sn2 And Sn )

    1623 Words  | 7 Pages

    Using various alcohols, the substitution reactions (Sn2 and Sn) were utilized by helping with which functional groups reacted, in which way. Developing a mechanism for the alcohols are discussed. This journal inspects the substitution reactions occurring in the alcohol-containing compounds. When a substitution reaction transpires, it substitutes one sigma (σ) bond with another sigma (σ) bond. In substitution reactions, there are two types that are focused when working with organic molecules, Sn1

  • Electrophilic Aromatic Substitution

    2520 Words  | 11 Pages

    Aromatic Substitution Reaction Justiniano, Priscilla Raiza N. School of Chemical Engineering and Chemistry, Mapua Institute of Technology, Intramuros, Manila, Philippines Experiment No.1, Submitted on August 6, 2011 at N402. Abstract EXPERIMENT NUMBER ONE IS ALL ABOUT THE ELECTROPHILIC SUBSTITUTION OF AROMATIC COMPOUNDS. AROMATIC COMPOUNDS ARE THOSE ORGANIC COMPOUNDS WHICH HAVE BENZENE RING (CYCLOHEXA-1,3,5-TRIENE). AROMATIC COMPOUNDS ARE ALWAYS FOLLOWS THE SUBSTITUTION REACTION BECAUSE

  • Nucleophilic Aromatic Substitution of 2,4-Dinitrochlorobenze Essay

    1766 Words  | 8 Pages

    Experiment #1 Nucleophilic Aromatic Substitution of 2,4-dinitrochlorobenze Name: Anouk Deck-Leger Student I.D: 9380868 Date performed: September 13th, 2010 Due Date: September 20th, 2010 Introduction: The company DNCB produces large amounts of 2,4-dinitrochlorobenzene and they sell this product to treat against warts and severe and chronic hair loss. It can also be used as an alternative treatment for HIV. The supervisor notices an excess amount of m-aminobenzoic acid stored away which

  • Relativities of Alkyl Halides in Nucleophilic Substitution Reactions

    647 Words  | 3 Pages

    Title: Relativities of Alkyl Halides in Nucleophilic Substitution Reactions Introduction: The purpose of this lab was to perform a comparison of relative reactivities of various alkyl halides with two different reagents, sodium iodine in acetone and silver nitrate in ethanol. (Below are the reaction equations). We used different substrates, which were primary, secondary, and tertiary. These substrates included 2-bromobutane, 2-bromo-2-methylpropane, 1-bromobutane ∞-Bromotoluene, bromobenzene

  • Electrophilic Aromatic Substitution Formal Lab Essay

    1635 Words  | 7 Pages

    Electrophilic Aromatic Substitution Objective The objective of this experiment was to illustrate electrophilic aromatic substitution by synthesizing p-nitroanilide (as well as ortho) from acetanilide by nitration. The para form was separated from the ortho form based on solubility properties using recrystallization techniques. Synthetic equations: Physical Properties & Hazards of Reagents/Products: (all taken from Sigma-Aldrich website) Acetanilide MM = 135.16 g/mol Melting point =

  • The Aromatic Substitution : Preparing Methyl M Nitrobenzene

    824 Words  | 4 Pages

    Electrophilic Aromatic Substitution: Preparing Methyl m-nitrobenzene Shultz, Joshua T. Chemistry 2210L Data Table 1. Mass and volumes of reagents and recovered product with experimental melting point. Reagents Mass/Volume Methyl Benzoate 1.50 mL Concentrated H2SO4 4.0 mL Concentrated HNO3 2.0 mL Products Mass Methyl m-nitrobenzoate 2.5607 g Experimental Melting Point 64-70 °C Results and Calculations Equation 1. Balanced reaction for nitration of methyl benzoate. Calculation 1. Theoretical

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