Suppository

Suppositories are the frequently used dosage forms prescribed through rectal route. However, suppositories have the limitation of prolonged onset of action which can be attributed to poor drug release properties of suppository base. Surfactants can increase the drug release to aid absorption by reducing the interfacial tension between rectal fluids and the suppository base. The objective of this study was to examine the effect of different concentrations of sodium lauryl sulphate and tween 80 on

shorter in the glycerin suppository group however it was not statistically significant. The study concluded that regular glycerin suppositories did not reduce the time to full enteral feeds in infants born at <32 weeks gestation and no significant differences were observed in secondary outcomes like incidence of sepsis, NEC, duration of oxygen requirement, growth or age at discharge. A double blinded RCT by Shinde, et al. concluded that once daily application of glycerin suppository does not accelerate

The earliest records of an abortive technique go back about 4,600 years to an ancient Chinese work, purportedly the work of Emperor Shen Nung which prescribes the use of mercury to induce an abortion. (3) In ancient ages pessaries or vaginal suppositories were used as an abortifacients.(1) They are generally more effective than oral drugs and included substances such as juice of the wild fig, a “dairy liquid” ,which caused irritation, soapwort, myrrh, myrtle, lupine, cedar-oil mixed with

Suppositories are solid, bullet shaped preparations administered via the anus. They usually consist of an active drug and a waxy, oily base which is able to soften at body temperature (37 °C). This will allow the drug to be released into the local environment and line the lower rectum, where it can be readily absorbed into the bloodstream [5]. Suppositories can be used for a variety of indications such as laxatives and pain relief. There are many advantages and disadvantages surrounding the use

Suppositories Rectal route with local or general effects is an interesting possibility of treatment. Easy use and rapid absorption are two major advantages. Hemorrhoids suppositories are a pretty old, mode of getting drugs into the body, and hemorrhoids suppositories are being used since Hippocrates, one of the founding fathers of Western medicine, who described a method of using reusable suppositories. Most suppositories these days aren’t meant to be reusable like the one described by him

female here F/U Pap smear result. C/O of frothy yellowish vaginal discharge with fishy odor, moderate amount, started a month ago, not getting better or worst. Fishy odor is more pronounce during sexual intercourse. Tried Monistat 200 mg vaginal suppository daily for 3 days a week ago, was not effective. Heterosexual, one sexual partner past 10 years, intermittent use of condoms. ROS General: Denies weight change, fatigue, fever, chills, night sweats, change in energy level Cardiovascular: Denies

Cannabis Sativa, also referred to as marijuana was founded by the “Father of Chinese Medicine”, Shen Nung in 2700 B.C. The medical use of marijuana has been around approximately thirty-two times longer than the oldest man-made pharmaceutical drug. Medical Marijuana has been undergoing extensive research over the course of the last decade to either give validity to all stereotypes surrounding the subject or proving the accusations false. Cannabis Sativa, has many forms of intake, it has been shown

• A suppository or enema given in the rectum to soften the stool, which can stimulate a bowel movement. HOME CARE INSTRUCTIONS Diet • Drink enough fluid to keep your urine clear or pale yellow. • Include a lot of fiber in your diet. Foods with a lot of fiber

by the staff. The resident reported that staff would laugh at him and say mean things to him such as, "We don't like you" and " Your wife does not like you.:" RP was also incontinent and needed assistance with suppositories; however, there were times where staff did insert the suppositories when the resident became "frozen." RP stated that there were times that staff assisted with the catheter insertion. It was reported that the resident was given a baby monitor for his room so that he could

transported into the hepatic portal vein for metabolism [8]. This means there is an increase in bioavailability in drugs absorbed in the lower rectum compared to the upper rectum. For this reason, a lower dose of drug can be used when formulating a suppository. This will be beneficial as there will be reduced costs for the manufacturer as well as the medicine and also less side effects for the patient which will result in better