Suppositories are the frequently used dosage forms prescribed through rectal route. However, suppositories have the limitation of prolonged onset of action which can be attributed to poor drug release properties of suppository base. Surfactants can increase the drug release to aid absorption by reducing the interfacial tension between rectal fluids and the suppository base. The objective of this study was to examine the effect of different concentrations of sodium lauryl sulphate and tween 80 on
culture and surfactant play in the formation of emulsions and biomass. Preparing the control treatment (no inoculum, no surfactant) was important because it established a method of comparison of the remaining experimental treatments and assessing whether or not the results obtained were rational. The experimental flask that was prepared as part of this experiment contained no inoculum and had surfactant addition. As indicated by the observations, demonstration flasks that contained surfactant had
Surfactant Replacement in Neonates with Respiratory Distress Syndrome Type The innovation of surfactant replacement therapy in the treatment of respiratory distress syndrome has proven to increase the survival and minimize the complications of the premature neonate. Replacing surfactant has lessened time on ventilators, and allowing the neonate and parents an opportunity to grow together earlier outside of intensive care. This paper will discuss the etiology of respiratory distress syndrome
Surfactant Replacement Therapy and the Affects on RDS and Other Pulmonary Disorders Jacquelyn M. Wood Grossmont Community College 2015 INTRODUCTION As a newborn makes their entrance to this world from intrauterine life all should go smoothly. The newborn is delivered and is stimulated to breathe and then is followed by inspirations, followed by a cry showing a successful arrival to this world, but not all deliveries go as planned. There are diseases of the respiratory system. The most
Surfactants! A surface active agent, also known as a surfactant is a substance that surrounds the inner surface of the lung and consists of four proteins and six phospholipid fats that are manufactured inside of the lung of the human body, however this substance can also be created artificially. The four proteins include the hydrophilic or water attracting proteins SP-A and SP-D and the opposite hydrophobic or water repelling proteins, SP-B and SP-C. The main purpose of a natural surfactant found
As of late, a lot of intrigue has been focussed on lipid based carries systems. The most prevalent approach is the fuse of the active poorly water dissolvable part into inert lipid vehicles, for example, oils, surfactant dispersions, solid dispersions, solid lipid nanoparticles, emulsions, micro emulsions, Nano emulsions, self-emulsifying plans (SEF), micro/nanoemulsifying formulations, and liposomes. The essential component of activity by which a lipid formulation prompts enhanced bioavailability
SOAPS AND DETERGENTS _DISCUSSION_ The goal of this project was to make, and test four soaps, and two detergents. The purpose of making four different soaps and two detergents was needed in order to decide which one would be best for the environmental group to use in the future that would allow for the safest cleanup of an oil spill while not harming the animals or the environment in the process. It was necessary to test the impact of the four soaps and two detergents by analyzing their different
A heating bath is used in the laboratory to allow the chemical reaction to occur at an elevated temperature around 1000C. The beaker is a glass vessel which contains the chemical solutions for the purpose of coating. It is placed in the electroless bath where the chemicals are being heated up. The glass rod is used to stir the chemical where the magnetic stirrer is not necessary. The tongs are used to lift the bath after the coating is completed. Tri-sodium citrate and thallium acetate are the chemicals
polystyrene nanoparticles were synthesized by a facile one-step emulsion polymerization technology using sodium dodecyl sulfonate (SDS) and 2, 2′-azobis (2-methylpropionamide) dihydrochloride (AIBA) as the surfactant and initiator, respectively. The in situ neutralization between negatively charged surfactant SDS and positively charged AIBA was used to control the primary particle (or swollen micelle) volume and the extent of the particle coagulation. As the oligomeric radicals with cationic AIBA chain ends
example in biological systems liposomes are formed whereas when bolaamphiphiles possess short alkyl chains they give micelles. The bolaform amphiphile is also less efficient than the conventional surfactants in lowering the surface tension of water. The values obtained from surface area per surfactant graphs suggest that most of the bolaforms take up a looped conformation at the interface, with the polar groups attached at the interface and alkyl chains forming a loop. It is also reported that the