Thalidomide

Introduction: In 1957 a German pharmaceutical company, Chemie Grunenthal produced the drug Thalidomide, that would impact the life of more than 10,000 babies worldwide. Originally this drug was produced and marketed as a sedative that was thought to be nearly impossible to over dose on. It was a cheap over the counter drug that was marketed to pregnant women because of its effectiveness of combating morning sickness. Over time this drug became very common throughout Europe, Oceanic Regions, and even

In the early 1950s, scientists at Chemie Grunenthal GmbH, a German pharmaceutical company developed a drug called Thalidomide. The drug was developed to treat respiratory infections and influenza however after getting minimal results they then decided to market the drug as a sleep aid and to treat morning sickness. Due to improper testing Thalidomide was released on the market and caused countless still births, miscarriages and tens of thousands of babies to be born with birth defects. (Lenz, 1988)

Thalidomide a once dangerous teratogen is now being used to treat cancer and inflammatory disease. Thalidomide was created in Germany and was sold in 46 different countries; it was originally intended to be a sedative but was later marketed towards pregnant women to help them cope with morning sickness. Thalidomide had an adverse effect causing birth defects. After the discovery of the birth defects being linked to thalidomide, the drug was pulled off the shelves to prevent further malformed babies

Thalidomide Essay By Chloe Mc Gee L00116537 (R)-Thalidomide (S)-Thalidomide The molecular formula for thalidomide is C13H10N2O4 and it has a molar mass of 258.23g/mol. Some of the trade names for thalidomide are thalomid, immunoprin, talidex and talizer. The main use of thalidomide today is mainly as a treatment for certain cancers and leprosy. Thalidomide was developed by a German firm called Chemie Grunenthal. It was first developed as an anticonvulsant drug, but failed to be effective as

Thalidomide Paper Thalidomide is a drug that was invented in Germany in the 1950’s. It was originally intended to treat respiratory infections but during testing, it was noted that the drug worked to relieve morning sickness for pregnant women. This new reason allowed the drug to be prescribed to many new patients all over the world. Eventually Thalidomide was discovered to be causing birth defects in all of the pregnant women that were taking it. It caused the fetus to not develop correctly by

Hannah Olsen Thalidomide Paper 12/14/15 Thalidomide was a drug made to treat many different health problems and is now known as one of the worst teratogens in history. Thalidomide is most well-known to help with morning sickness in pregnant women, but that’s not what its original purpose was. The original purpose of thalidomide was to use for respiratory problems. Another use of thalidomide that was practiced was to “provide a safe sound sleep” (Thalidomide Victims Association of Canada, n.d.)

Thalidomide was a drug created for pregnant women in 1957.It was first introduced on the market in west Germany on October 1, 1957. It was created to help combat symptoms associated with women 's morning sickness, but it caused more harm than good. It created a worldwide epidemic. It was created as a harmless sleeping pill. Thalidomide created many birth defects affecting 10,000 children worldwide like phocomelia and Amelia . Thalidomide could be bought without a prescription from the doctor in west

Children of Thalidomide, a name given to the group of about 10,000 infants to be born with phocomelia, a deformity in which limbs are attached to close to the trunk, the limbs being grossly underdeveloped or absent. The deformity caused by a drug by the name of Thalidomide. The tragedy shook many, earning it a spot in Billy Joel’s smash hit “We Didn’t Start the Fire”. The lyrics of the song chronicle important events or people starting from the year 1949 and ending in 1989, the year the song was

Ideally biopsies of abdominal subcutaneous tissue and salivary glands should be used for the Congo red staining test, and it is positive if the sample has apple-green birefringence in appearance under polarized light. If the sample was inconclusive or negative, then the provider should have the affected organ biopsied to ensure an accurate diagnosis. The reason one should investigate for amyloid deposits via more invasive biopsy techniques is due to the higher risk of mortality associated with misdiagnosis

still the same. So scientists back then have not discovered that there can be more than one isomer of thalidomide, where a women may receive the thalidomide with the ‘good isomer’ where it will do no harm to the women’s baby or where the women may receive the ‘bad isomer’ which will cause the deformities. It was rather just a chance of whether you get the good or bad version of the thalidomide. The isomers may have different variations in their bonding where it can just be a single bond is saturated