Answered: . Can a missense mutation of proline to…

Name: . Can a missense mutation of proline to histidine bemade with a G • C
Uploaded: 2024-03-20T06:42:55.000Z
Channel: Bartleby
Description: . Can a missense mutation of proline to histidine bemade with a G • C → A • T transition-causing mutagen?What about a proline-to-serine missense mutation?

Science

Biology

. Can a missense mutation of proline to histidine bemade with a G • C → A • T transition-causing mutagen?What about a proline-to-serine missense mutation?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 10QP: If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense...

See similar textbooks

Similar questions

a. Why is it impossible to induce nonsense mutations(represented at the mRNA level by the triplets UAG,UAA, and UGA) by treating wild-type strains with mutagens that cause only A• G → T• C transitions in DNA?b. Hydroxylamine (HA) causes only G• C → A• T transitions in DNA. Will HA produce nonsense mutations inwild-type strains?c. Will HA treatment revert nonsense mutations?
PLEASE ANSWER WHY? Some substitution mutation result in a malfunctioning protein but others do not. Why is this?
Explain why a point mutation does not necessarily change the oriignal amino acid sequence. Explain silent mutations.
What is a transposon? Explain why the insertion of a transposon into the DNA of a cell can lead to a mutation
Some substitution mutation result in a malfunctioning protein but others do not. Why is this?
Pls briefly describe point mutation.
Do you think each of the following types of mutationswould have very severe effects, mild effects, or no effectat all?a. Nonsense mutations occurring in the sequences encoding amino acids near the N terminus of the proteinb. Nonsense mutations occurring in the sequences encoding amino acids near the C terminus of the proteinc. Frameshift mutations occurring in the sequences encoding amino acids near the N terminus of the protein d. Frameshift mutations occurring in the sequencesencoding amino acids near the C terminus of theproteine. Silent mutationsf. Conservative missense mutationsg. Nonconservative missense mutations affecting theactive site of the proteinh. Nonconservative missense mutations not in the active site of the protein
using example what is a degenerate primer? with the aid of diagrams discuss how degenerate primers are used to introduce random mutations in a gene and list some advantages and disadvantages of generating modified protein by this method .
Discuss the difference between frameshift vs. substitution mutation and give an example of how frameshift can completely damage a protein while substitution could have no effect on the protein made.
What is the resulting polypeptide: _______________________________________________________? What effect does this mutation have on the polypeptide? Make sure to compare to the original polypeptide. Is this more or less harmful than the previous mutation in step #10? Why?
Consider the tryptophan codon 5′ - UGG - 3′ in the standard genetic code . Can a single base change in this codon create a synonymous mutation? Can a single base change in this codon create a nonsense codon?
Correct! The Leu codon is changed to a nonsense codon by a single-base substitution How many different ways can the LEU codon be changed into the nonsense mutation? 362110