1) Based upon the above data, what is the most likely cause of Joseph's medical emergency? 2) What is the clinical significance of the slightly cloudy CSF?
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The youngest member of the Doe family, 18-month-old Joseph, is rushed to the emergency department with a fever of 103F and lethargy. As part of the diagnostic assessment, a CSF sample was collected. Macroscopic, cellular, and biochemical results for this sample are as follows:
CSF Colo: colorless
CSF Clarity: slightly cloudy
CSF WBC Count: 95 cells/L- predominantly macrophages and lymphocytes
CSF RBC Count: 2 cells/L
CSF Total Protein: 72 mg/dL
Plasma Total Protein: 6.8 g/dL
CSF Glucose: 55 mg/dL
Plasma Glucose: 90mg/dL
1) Based upon the above data, what is the most likely cause of Joseph's medical emergency?
2) What is the clinical significance of the slightly cloudy CSF?
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- Mary Brown [MB] is a healthy 36-year-old woman with complaints of persistent generalized fatigue. At her annual checkup, her vital signs: heart rate (HR), 118 beats/min; blood pressure (BP), 110/60 mm Hg; oral temperature, 37°C; and respiratory rate (RR), 26 breaths/min. Her skin, conjunctiva and nail beds are pale. Laboratory results: hematocrit (Hct), 27%; hemoglobin (Hb), 9 g/dL and hypochromatic red blood cells (RBCs) are present. What other history data would be helpful in determining the cause of this disorder?Mary Brown [MB] is a healthy 36-year-old woman with complaints of persistent generalized fatigue. At her annual checkup, her vital signs: heart rate (HR), 118 beats/min; blood pressure (BP), 110/60 mm Hg; oral temperature, 37°C; and respiratory rate (RR), 26 breaths/min. Her skin, conjunctiva and nail beds are pale. Laboratory results: hematocrit (Hct), 27%; hemoglobin (Hb), 9 g/dL and hypochromatic red blood cells (RBCs) are present. Which of MB’s clinical signs are reflective of the body’s effort to compensate for the decreased oxygen carrying capacity seen with this condition?Mary Brown [MB] is a healthy 36-year-old woman with complaints of persistent generalized fatigue. At her annual checkup, her vital signs: heart rate (HR), 118 beats/min; blood pressure (BP), 110/60 mm Hg; oral temperature, 37°C; and respiratory rate (RR), 26 breaths/min. Her skin, conjunctiva and nail beds are pale. Laboratory results: hematocrit (Hct), 27%; hemoglobin (Hb), 9 g/dL and hypochromatic red blood cells (RBCs) are present. MB is counseled to increase her dietary intake of iron-containing foods. What kinds of food would be recommended?
- A 12-weeks pregnant woman complains of inability to focus, fatigue, and shortness of breath. On a physical examination, she looks pale and weak. Laboratory results are as follows: Reticulocyte count: 1%, Hematocrit: 27%; Hemoglobin: 6.5 g/dL; MCV: 105 fL, MCHC: 32%. Does this patient need a transfusion? JustifyMary Brown [MB] is a healthy 36-year-old woman with complaints of persistent generalized fatigue. At her annual checkup, her vital signs: heart rate (HR), 118 beats/min; blood pressure (BP), 110/60 mm Hg; oral temperature, 37°C; and respiratory rate (RR), 26 breaths/min. Her skin, conjunctiva and nail beds are pale. Laboratory results: hematocrit (Hct), 27%; hemoglobin (Hb), 9 g/dL and hypochromatic red blood cells (RBCs) are present. What type of hematologic disorder would you suspect based on MB’s laboratory values? Why?A 12-weeks pregnant woman complains of inability to focus, fatigue, and shortness of breath. On a physical examination, she looks pale and weak. Laboratory results are as follows: Reticulocyte count: 1%, Hematocrit: 27%; Hemoglobin: 6.5 g/dL; MCV: 105 fL, MCHC: 32%. Does this patient need a transfusion? Justify your answer.
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