2 DA Metformin is often the first drug prescribed to treat high glucose levels in blood associated with diabetes type 2. We don't know the macromolecular targets of metformin, only that metformin reduces glucose absorption by the intestine and modestly suppresses gluconeogenesis. Other drugs, sometimes used in combination with metformin, suppress liver gluconeogenesis significantly. What side effect is likely? Lactic acidosis Tourette syndrome Agoraphobia Atrial fibrillation
2 DA Metformin is often the first drug prescribed to treat high glucose levels in blood associated with diabetes type 2. We don't know the macromolecular targets of metformin, only that metformin reduces glucose absorption by the intestine and modestly suppresses gluconeogenesis. Other drugs, sometimes used in combination with metformin, suppress liver gluconeogenesis significantly. What side effect is likely? Lactic acidosis Tourette syndrome Agoraphobia Atrial fibrillation
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter22: Gluconeogenesis, Glycogen Metabolism, And The Pentose Phosphate Pathway
Section: Chapter Questions
Problem 8P
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3
DO
Metformin is often the first drug prescribed to treat high glucose levels in blood associated with diabetes type 2. We don't know the macromolecular targets of metformin, only
that metformin reduces glucose absorption by the intestine and modestly suppresses gluconeogenesis. Other drugs, sometimes used in combination with metformin, suppress
liver gluconeogenesis significantly. What side effect is likely?
O Lactic acidosis
O Tourette syndrome
Agoraphobia
O Atrial fibrillation
Which activities in liver are enhanced by glucagon?
Conversion of glycogen to Glc-1-P.
Conversion of glycogen synthase b to glycogen synthase a.
Conversion of Fru-6-P to Fru-2,6-P2.
Conversion of Fru-6-P to Fru-1,6-P₂.
DO](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F61158d8e-2286-4925-baa4-79c8980c32cb%2F7b18891a-279b-4da6-8350-82ea6273b43b%2F0ymxw4s_processed.png&w=3840&q=75)
Transcribed Image Text:2
3
DO
Metformin is often the first drug prescribed to treat high glucose levels in blood associated with diabetes type 2. We don't know the macromolecular targets of metformin, only
that metformin reduces glucose absorption by the intestine and modestly suppresses gluconeogenesis. Other drugs, sometimes used in combination with metformin, suppress
liver gluconeogenesis significantly. What side effect is likely?
O Lactic acidosis
O Tourette syndrome
Agoraphobia
O Atrial fibrillation
Which activities in liver are enhanced by glucagon?
Conversion of glycogen to Glc-1-P.
Conversion of glycogen synthase b to glycogen synthase a.
Conversion of Fru-6-P to Fru-2,6-P2.
Conversion of Fru-6-P to Fru-1,6-P₂.
DO
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