36. Which is the major product of the following reaction? Br₂ light A. Br B. D. E. Br Br C. Br Br 37. Which conditions favor an efficient (fast, high yield) SN2 reaction between an appropriate alkyl halide and a nucleophile with a charge? A. high concentration of a strong nucleophile, polar aprotic solvent B. high concentration of a weak nucleophile, nonpolar solvent C. low concentration of a strong nucleophile, polar aprotic solvent D. low concentration of a weak nucleophile, nonpolar solvent E. high concentration of a strong nucleophile, nonpolar solvent

Which member of each pair is a better nucleophile in methanol? a. H2O or HO- b. NH3 or H2O c. H2O or H2S  d. I- or Br- e. HO- or HS- f. Cl- or Br-

Which is a better nucleophile? a. Br or C in H20 b. Br or CI in DMSO c. CH3O or CH;OH in H20 d. CH30 or CH3OH in DMSO e. HO or NH2 in H20 f. HO or NH, in DMSO g. F or Br in H20 h. I or Br in DMSO

Rank the nucleophiles in each group in order of increasing nucleophilicity.a. -OH, -NH2, H2Ob. -OH, Br-, F- (polar aprotic solvent)c. H2O, -OH, CH3CO2-

Which species is likely to undergo a reaction with the nucleophile readily? A. (ch3)3cl b. (Ch3)2HCI c. Ch3ch2cl d. CH3CI

Draw the substitution product that results when CH,CH2CH;CH,Br reacts with each nucleophile. d. "OCH(CH3)2 e. "C=CH f. H20 a. "OH g. NH3 b. "SH h. Nal c. "ČN i. NaNg

Rank the following species in each set from best nucleophile to poorest nucleophile.

Identify the nucleophile and leaving group and draw the products of each substitution reaction.

3. Draw the carbocation intermediate that the halide must attack to form the given product for each of the reactions below. a. b. ن d. Br Br Br Br 2 پر مشو

Benzyl chloride is reacted with different nucleophiles (HO-, CH3COO-, PhO-, CH3O-). Arrange them in the decreasing order of reactivity with benzyl chloride. A. CH3O¯> HO- > PhO-> CH3CO0- B. HO->CH3O-> PhO> CH3CO0- C. HO-> PhO- > CH3O¯> CH3C- D. CH3COO-> CH³O¯> HO-> PhO- Note: benzyl chloride PhO, phenoxide