A mouse fibroblast cell line in culture was treated with a compound derived from a fungus, which caused the cells to stop dividing. In order to understand how this compound inhibits cell division, a culture of these cells was grown and treated with the compound, and cell samples were taken at increasing times after addition of the compound. The cells in each sample were stained with a fluorescent DNA-binding dye and analyzed by flow cytometry. Data are shown below for four cell samples taken at 0, 5, 16, and 24 hours after addition of the compound. Fluorescence intensity is shown on the x-axis and cell number on the y-axis. Cell number Oh 24 h التالي 200 16 h 5 h I 100 200 250 0 100 200 250 0 100 200 200 250 0 100 200 250 Fluorescence In 2-3 sentences, explain which cell cycle phase is blocked by the compound, and how you came to that conclusion.

A mouse fibroblast cell line in culture was treated with a compound derived from a fungus, which caused the cells to stop dividing. In order to understand how this compound inhibits cell division, a culture of these cells was grown and treated with the compound, and cell samples were taken at increasing times after addition of the compound. The cells in each sample were stained with a fluorescent DNA-binding dye and analyzed by flow cytometry. Data are shown below for four cell samples taken at 0, 5, 16, and 24 hours after addition of the compound. Fluorescence intensity is shown on the x-axis and cell number on the y-axis. Cell number Oh 24 h التالي 200 16 h 5 h I 100 200 250 0 100 200 250 0 100 200 200 250 0 100 200 250 Fluorescence In 2-3 sentences, explain which cell cycle phase is blocked by the compound, and how you came to that conclusion.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter28: Dna Metabolism: Replication, Recombination, And Repair

Section: Chapter Questions

Problem 19P: Figure 28.11 depicts the eukaryotic cell cycle. Many cell types â€œexitâ€� the cell cycle and...

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