A mutant has no activity for the enzyme isocitrate lyase.Does this result prove that the mutation is in the geneencoding isocitrate lyase?

Q: Can nonsense mutations be reversed by hydroxylamine? Why or why not?

A: Mutations are the events that results in change in the DNA sequence. Mutations can be a result of…

Q: What characteristics are most commonly found in rho-independent terminators?

A: Terminator is a segment of nucleic acid sequence. In the process of transcription, the terminator…

Q: What are Effects of deletions in the β-globin gene ?

A: β-globin locus includes five genes that are located on a short region of the chromosome-11. It is…

Q: "The molecule serving as the genetic material is expected to absorb at the wavelengths shown to be…

A: DNA is a double-stranded molecule with helical structure. It has made of nucleotides containing four…

Q: Another class of suppressor mutations, not describedin the chapter, are mutations that suppress…

A: A missense mutation is a type of mutation in which the error occurs in a single base. It is also…

Q: what are disease-causing mutations? Explain with  suitable exaamples

A: Mutations are the alterations or the changes that occur in the DNA. Mutagens are the agents that are…

Q: What would happen to the regulation of the tryptophan operon in bacterial cells that express a…

A: In E. coli, all the 20 amino acids can be synthesized in vivo by the organism. The genes for the…

Q: What are deletion mutation with suitable example?

A: Mutations are the alterations or the changes that occur in the DNA. Mutations are variations in…

Q: How can the bacteriophage T7 promoter be used to controlexpression of a eukaryotic gene in…

A: Expression vectors are designed to control the expression of particular cloned genes. The native…

Q: What is the significance of the terminal inverted repeats oftransposons?

A: Transposons are the sequences of the nucleotides in the genome that have the ability to change their…

Q: A gene contains eight sites where alternativesplicing is possible. Assuming that the splicing…

A: according to the question, A gene contains eight sites where alternative splicing is possible:

Q: What is a A hypomorphic mutation?

A: The change in normal structure or function of a wild type of gene due to alteration in nucleotides,…

Q: What are histone deacetylase inhibitors (HDACi)? Give example(s)

A: Histone deacetylase (HDAC) is an accelerator that removes the acetyl radical from histone proteins…

Q: Why is there some signal present within the ‘no sugar’ and other noninducing sugars for the green…

A: The L-arabinose operon, commonly known as the ara operon, is a gene sequence that encodes enzymes…

Q: Does a gene sequence carry a mutation that might cause adisease?

A: Mutation is defined as any sudden change in the nucleotide sequence of genes. It may also be defined…

Q: What is the difference between a missense mutation and a nonsense mutation?

A: Mutation is defined as the sudden and permanent change in the nucleotide sequence of DNA. It causes…

Q: Why would a mutation in a somatic cell of a multicellular organism escape detection?

A: Mutations that likely occurred in a somatic cell are not supposed to be transferred to its next…

Q: . What type of mutation of the lac repressor might be both constitu- tive and trans-dominant?

A: Trans-Dominant- A mutation in a regulatory gene that can control the expression of a structural gene…

Q: A gene contains eight sites where alternative splicing is possible. Assuming that the splicing…

A: Given :  A gene contains eight sites where alternative splicing is possible. To find : The splicing…

Q: The E. coli genome contains approximately 4639 kb. (a) How many copies of the 6-bp recognition…

A: E.coli is a type of bacteria that normally lives in the intestine. It is also found in the gut of…

Q: Where metal-inducible transcription factor 1 (MTF-1) is found ?

A: Metal regulatory transcription factor-1 or metal inducible transcription factor-1 plays a role in…

Q: What would be the consequences if a mutation removed the rut site from this RNA molecule?

A: Mutation is an abrupt change in the DNA sequence and nucleotide base pairs.  Mutation is caused by…

Q: How can the binding assay technique be used to assign coding triplets to the corresponding amino…

A: Different triplet corresponds to different amino acids. In this method, an amino acid that is…

Q: What mutagen causes thymine dimers, and why does it kill cells?

A: A mutation occurs/happens when the sequence/structure of DNA changes. Mutations can occur/happens as…

Q: Why in some instances are cytosines mutational hotspots?

A: Throughout a nucleotide sequence, mutation frequencies vary. Mutation "hotspots" are positions where…

Q: Assume that a mutation occurs in the gene that encodes RNA pol II. What would be the effect of the…

A: A "nucleic acid" is a linear polymer of nucleotides that is a component of the cell's information…

Q: Why is the trp attenuation mechanism unique to prokaryotes?

A: Attenuation is a control mechanism that operates to regulate the expression of genes of an operon.…

Q: How can we identify histone modifications?

A: Histones are the class of proteins which are associated with the DNA in the nucleus and aids in the…

Q: What would be the phenotype of an E. coli strain in which the tandem tryptophan codons in the leader…

A: The set of genes controlled by a single promoter or regulatory sequence associated with that…

Q: . Why is a nonsense suppressor tRNATyr, even though ithas a mutant anticodon that cannot recognize a…

A: The aminoacyl-tRNA synthetases have recognition sites for amino acids, ATP (Adenosine triphosphate),…

Q: . Can a missense mutation of proline to histidine bemade with a G • C → A • T transition-causing…

A: A missense mutation is a point mutation that occurs in a codon that codes for a different amino acid…

Q: What mutagen results to the formation of thymine dimers?

A: Asked : Mutagen which results to the formation of thymine dimers

Q: What is known as catabolite repression ?

A: Certain terms are fundamental concepts and terms used in biology, which is the study of life and…

Q: An individual carries a somatic mutation that changes a lysinecodon into a glutamic acid codon.…

A: A mutation is an alteration or change in a deoxyribonucleic acid (DNA) sequence. Mutations can…

Q: For RNA Plymerase type two generated transcripts in eukaryotes, how polyadenylation is linked with…

A: The poly-A tail makes the RNA molecule more stable and prevents its degradation. Additionally, the…

Q: What is the role of the lacZ gene product, the enzyme B-galactosidase?

A: An operon is a functional unit of DNA (Deoxyribonucleic acid) containing a cluster of genes under…

Q: What is the probability that the palindromic symmetry of the trp repressor target DNA sequence is…

A: Palindromic sequences are the sequences present in the DNA double helix that are read the same from…

Q: Consider the expression “central dogma,” which refers to the flow of genetic information from DNA to…

A: The transfer of genetic data in cells from DNA to messenger RNA (mRNA) to protein is described by…

Q: How does the tryptophan operan turn back on in gene regulation?

A: Bacteria like Escherichia coli (a benign tenant of our gut) need amino acids to survive since they,…

Q: How would a null mutation in the guanylyl transferase gene affect overall mRNA stability in…

A: RNA guanylyltransferase is known as a capping enzyme. It catalyzes the transfer of GMP from GTP to…

Q: What is the frequency of loss-of-function mutations in ADE2 when specific (HDR) and non-specific…

A: Each pathway, including the non-homologous end joining (NHEJ), resulted in a 50% reduction in…

Q: For the ovalbumin gene where would the 5′ untranslated region and 3′ untranslated regions be located…

A: Nuclei acids consist of a sequence of nucleotides, which provides information for protein production…

Q: Why are frameshift mutations likely to be more detrimental than point mutations, in which a single…

A: A mutation is a permanent change in the DNA of a cell such that the sequence deviates from what is…

Q: Why are there no Pol I mutants that completely lack 5′ → 3′ exonucleaseactivity?

A: Exonuclease is considered as the enzyme, which cleaves the DNA fragment from the outer end sides.

Q: A transposable element is found to encode a reverse transcriptase enzyme. On the basis of this…

A: Transposable elements are known as stretches of DNA molecules and they can move from one place to…

Q: Explain the Mutations at the Huntington disease locus are caused by an expansion of a trinucleotide…

A: Huntington’s disease is a brain disorder that is inherited in an autosomal dominant pattern. It is…

Viral Replication

The virus is acellular and considered non-living outside the host cell. The replication of the virus occurs only inside the living cells. Only a few genes are present in the smallest virus, whereas many genes are present in the largest virus. These genes encode specific viral proteins.