β-globin gene indicate that some areas are more sensitive than others. When mutations occur in consensus sequences (modular elements such as GC box, CAAT box, TATA box), transcription usually A. increases b. stays about the same c. decreases

β-globin gene indicate that some areas are more sensitive than others. When mutations occur in consensus sequences (modular elements such as GC box, CAAT box, TATA box), transcription usually A. increases b. stays about the same c. decreases

Name: Mutations in the promoter region of the β-globin gene indicate that so
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Description: Mutations in the promoter region of the β-globin gene indicate that some areas are more sensitive than others. When mutations occur in consensus sequences (modular elements such as GC box, CAAT box, TATA box), transcription usuallyA. increases

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter14: Gene Regulation

Section: Chapter Questions

Problem 8TYU: Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription...

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A transcription factor (protein - orange/green) is bound to a promoter of a gene (DNA - blue) it regulates. What changes would result in the gene not being expressed? A. Mutations in the DNA sequence where the TF is bound B. Mutations in the DNA binding domain of the TF C. Mutations in the 3’UTR (untranslated region) of this gene  A and B only  B and C only  A, B, and C
1. Transcription: a)State the role of RNA polymerase in gene transcription.b. Explain why the DNA is not used directly for protein translation (i.e., why is mRNA used instead?).c. Explain what occurs when a gene’s promoter region is open for RNA polymerase binding.d. Explain what occurs when a gene’s promoter regions is blocked from binding RNA polymerase.e. Explain how two cells, such as liver cells and skin cells, can become specialized in structure and function despite containing the same genome.
a. Show (on the image) 3 steps that must be taken to produce a mature mRNA molecule from this pre- mRNAb. Place an arrow at the 5’ end of intron 2. (splice site). c. Why is a promoter not shown in this image?
Which of these is used in the transcription of all genes? Choose all correct answers. A. Core promoter B. Proximal promoter C. Distal promoter D. General Transcription Factors E. Regulatory Transcription Factors
Which of the following is not true regarding gene regulation that involves DNA bending? a. The precise distance between the regulatory sequence and the promoter is important. b. Effect can be to repress transcription c. Effect can be to activation transcription d. Regulated genes can be thousands of base pairs away from the regulatory sites
Which of the following is true of CpG islands? a. They are methylated near promoters of actively transcribed genes. b. They are unmethylated near promoters of actively transcribed genes. c. Acetylation of CpG islands leads to repression of transcription. d. CpG islands code for RNA molecules that activate transcription.
Which of the following is false regarding the role of mediator complex in eukaryotic transcription initiation? a. Mediator complex interacts with RNA pol II b. Mediator binds to upstream enhancer sequences c. Mediator interacts with general transcription factors d. Mediator interacts with transcriptional activators e. All of the above are true about the mediator complex
Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription of heterochromatin (c) produce related but different proteins in different tissues (d) amplify genes to meet the requirement of high levels of a gene product (e) bind transcription factors to enhancers to activate transcription
The TATA box binding protein binds to the TATA box. What is the DNA sequence of this region of the promoter? Select one: a. Unknown. b. AAUAAA C. AUG d. KDEL e. TATA
Which of the following activities DOES NOT happen during the initiation stage of transcription? A. Use of RNA polymerase. B. Detection of TATA-box C. Attachment of transcription factors D. Addition of G' Cap and Poly-A tail A section of DNA has the following sequence of nitrogenous bases: CGATTACAG. Which of the following sequence would be produced as a result of transcription? A. CGTUUTCTG B. GCTAATGTC C. CGAUUACAG D. GUAAUGUC
Give one example of a prokaryotic system of gene expression that is more complicated (duringtranscription at the promoter) than its corresponding eukaryotic system of gene expression.A. prokaryotes require general transcription factors to initiate transcriptionB. prokaryotes typically have activator and repressor DNA sequences thousands of nucleotides awayC. prokaryotes have three classes of RNA polymerasesD. prokaryotes always have their DNA tightly packed into higher-level structures than nucleosomesE. prokaryotes usually have polycistronic mRNA
1. The following image shows a mechanism in which gene expression activity is regulated by ligand. Arg RS-2 Teu Met RBS Ligand RBS hidden a. What is this kind of regulatory machnism called? b. Does it involve transcription or translation? c. What happens in the presence of the ligand? d. What happens in the absence of theligand? e. What do you think the genes that are regulated here - metabolic (breakdown) or anabolic (buildup) for the ligand? Explain