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9.
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- Explain why Griffith’s mixture of harmless dead bacteria possessing capsules and harmless live bacteria lacking capsules is pathogenicGiven that both human cells and pathogens synthesize proteins at ribosomal sites, how can antimicrobial agents that target this process be safe to use in humans?Below, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?
- Can you think of a situation in which it would be better for a drug to be microbistatic rather than microbicidal? Discuss thoroughly.Define sterilant, and name the principal sporicidal chemical agents.Could an organism that is susceptible to an antimicrobial agent in laboratory testing fail to respond to it when that drug is used to treat the patient? Explain.