Define the meaning of the term "peptic ulcer disease". Discuss some of the risk factors that make people susceptible (including factors that protect the mucosa of the stomach/duodenum and those that cause damage to it. ANSWER SHOULD INCLUDE: Accurate definition, e.g. mucosa break greater than 3-5mm in the stomach or duodenum with a visible depth. Discussion of factors e.g. infections (H. Pylori; others mainly in immunocompromised patients, e.g. cytomegalovirus ,tuberculosis, and syphilis), gastric bypass surgery, cigarette smoking, medication/drugs, physiological stress associated with critical illness (e.g. septicaemia), autoimmune diseases, eg, vasculitis, sarcoidosis, Crohn's disease. Discussion of factors e.g. protection: bucarb, blood flow, prostaglandin, mucus. Damage: H. Pylori, gastric acid, pepsin, drugs e.g. NSAID
Define the meaning of the term "peptic ulcer disease". Discuss some of the risk factors that make people susceptible (including factors that protect the mucosa of the stomach/duodenum and those that cause damage to it.
ANSWER SHOULD INCLUDE:
Accurate definition, e.g. mucosa break greater than 3-5mm in the stomach or duodenum with a visible depth.
Discussion of factors e.g. infections (H. Pylori; others mainly in immunocompromised patients, e.g. cytomegalovirus ,tuberculosis, and syphilis), gastric bypass surgery, cigarette smoking, medication/drugs, physiological stress associated with critical illness (e.g. septicaemia), autoimmune diseases, eg, vasculitis, sarcoidosis, Crohn's disease.
Discussion of factors e.g. protection: bucarb, blood flow, prostaglandin, mucus. Damage: H. Pylori, gastric acid, pepsin, drugs e.g. NSAID
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