Drug X has the following properties: Multiple H bond donors and acceptors, a low log P, a low solubility in octan-1-ol, low molecular weight and contains both amino and carboxylic acid functional groups. Which of the following statements about the predicted oral bioavailability is TRUE? A. The drug will likely utilise the passive transcellular pathway. B. The drug will probably display increased oral bioavailability when taken after a high fat meal C. The drug resembles an amino acid and could be absorbed by the folate transporter D. The low logP suggests extensive partitioning into the phospholipid bilayer of the small intestinal mucosa E. The drug could be absorbed by the amino acid transporters expressed in the small intestine

Drug X has the following properties: Multiple H bond donors and acceptors, a low log P, a low solubility in octan-1-ol, low molecular weight and contains both amino and carboxylic acid functional groups. Which of the following statements about the predicted oral bioavailability is TRUE? A. The drug will likely utilise the passive transcellular pathway. B. The drug will probably display increased oral bioavailability when taken after a high fat meal C. The drug resembles an amino acid and could be absorbed by the folate transporter D. The low logP suggests extensive partitioning into the phospholipid bilayer of the small intestinal mucosa E. The drug could be absorbed by the amino acid transporters expressed in the small intestine