dsDNA viruses can have more genetic material than SSRNA viruses because: a. RNA catalyzes its own hydrolysis. b. A second strand improves the stability of nucleotides c. DNAS have improved stability and lower mutation rates because of host repair proteins. d. The extra hydroxyl group makes RNA more energetically expensive for host cells.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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**Question 7: Why dsDNA Viruses Can Have More Genetic Material Than ssRNA Viruses**

Double-stranded DNA (dsDNA) viruses can have more genetic material compared to single-stranded RNA (ssRNA) viruses due to several factors:

a. **RNA Catalyzes Its Own Hydrolysis**  
   RNA molecules are prone to self-hydrolysis, which can limit the stability and size of ssRNA genomes.

b. **A Second Strand Improves the Stability of Nucleotides**  
   The presence of a second strand in dsDNA provides additional stability to the nucleotide sequence, making the genetic material less susceptible to degradation.

c. **DNAs Have Improved Stability and Lower Mutation Rates Because of Host Repair Proteins**  
   DNA benefits from cellular repair mechanisms that help maintain genetic integrity, resulting in lower mutation rates compared to RNA.

d. **The Extra Hydroxyl Group Makes RNA More Energetically Expensive for Host Cells**  
   RNA contains an extra hydroxyl group, which is energetically more demanding for host cells to maintain, potentially limiting the size of RNA genomes.
Transcribed Image Text:**Question 7: Why dsDNA Viruses Can Have More Genetic Material Than ssRNA Viruses** Double-stranded DNA (dsDNA) viruses can have more genetic material compared to single-stranded RNA (ssRNA) viruses due to several factors: a. **RNA Catalyzes Its Own Hydrolysis** RNA molecules are prone to self-hydrolysis, which can limit the stability and size of ssRNA genomes. b. **A Second Strand Improves the Stability of Nucleotides** The presence of a second strand in dsDNA provides additional stability to the nucleotide sequence, making the genetic material less susceptible to degradation. c. **DNAs Have Improved Stability and Lower Mutation Rates Because of Host Repair Proteins** DNA benefits from cellular repair mechanisms that help maintain genetic integrity, resulting in lower mutation rates compared to RNA. d. **The Extra Hydroxyl Group Makes RNA More Energetically Expensive for Host Cells** RNA contains an extra hydroxyl group, which is energetically more demanding for host cells to maintain, potentially limiting the size of RNA genomes.
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